Format

Send to:

Choose Destination

IL12B interleukin 12B [ Gallus gallus (chicken) ]

Gene ID: 404671, updated on 14-Feb-2019

Summary

Symbol
IL12Bprovided by CGNC
Full Name
interleukin 12Bprovided by CGNC
Primary source
CGNC:966
See related
Ensembl:ENSGALG00000001409
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
IL-12B; IL-12p40
Orthologs

Genomic context

See IL12B in Genome Data Viewer
Location:
chromosome: 13
Exon count:
10
Annotation release Status Assembly Chr Location
104 current GRCg6a (GCF_000002315.5) 13 NC_006100.5 (8854550..8879511)
103 previous assembly Gallus_gallus-5.0 (GCF_000002315.4) 13 NC_006100.4 (8133046..8158041)
102 previous assembly Gallus_gallus-4.0 (GCF_000002315.3) 13 NC_006100.3 (7492735..7498870)

Chromosome 13 - NC_006100.5Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107054502 Neighboring gene adrenoceptor alpha 1B Neighboring gene uncharacterized LOC101747476 Neighboring gene serine protease inhibitor Kazal-type 6-like Neighboring gene F-box protein 38

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from BioSystems

  • Cytokine-cytokine receptor interaction, organism-specific biosystem (from KEGG)
    Cytokine-cytokine receptor interaction, organism-specific biosystemCytokines are soluble extracellular proteins or glycoproteins that are crucial intercellular regulators and mobilizers of cells engaged in innate as well as adaptive inflammatory host defenses, cell ...
  • Cytokine-cytokine receptor interaction, conserved biosystem (from KEGG)
    Cytokine-cytokine receptor interaction, conserved biosystemCytokines are soluble extracellular proteins or glycoproteins that are crucial intercellular regulators and mobilizers of cells engaged in innate as well as adaptive inflammatory host defenses, cell ...
  • Herpes simplex infection, organism-specific biosystem (from KEGG)
    Herpes simplex infection, organism-specific biosystemHerpes simplex virus (HSV) infections are very common worldwide, with the prevalence of HSV-1 reaching up to 80%-90%. Primary infection with HSV takes place in the mucosa, followed by the establishme...
  • Herpes simplex infection, conserved biosystem (from KEGG)
    Herpes simplex infection, conserved biosystemHerpes simplex virus (HSV) infections are very common worldwide, with the prevalence of HSV-1 reaching up to 80%-90%. Primary infection with HSV takes place in the mucosa, followed by the establishme...
  • Influenza A, organism-specific biosystem (from KEGG)
    Influenza A, organism-specific biosystemInfluenza is a contagious respiratory disease caused by influenza virus infection. Influenza A virus is responsible for both annual seasonal epidemics and periodic worldwide pandemics. Novel strains ...
  • Influenza A, conserved biosystem (from KEGG)
    Influenza A, conserved biosystemInfluenza is a contagious respiratory disease caused by influenza virus infection. Influenza A virus is responsible for both annual seasonal epidemics and periodic worldwide pandemics. Novel strains ...
  • RIG-I-like receptor signaling pathway, organism-specific biosystem (from KEGG)
    RIG-I-like receptor signaling pathway, organism-specific biosystemSpecific families of pattern recognition receptors are responsible for detecting viral pathogens and generating innate immune responses. Non-self RNA appearing in a cell as a result of intracellular ...
  • RIG-I-like receptor signaling pathway, conserved biosystem (from KEGG)
    RIG-I-like receptor signaling pathway, conserved biosystemSpecific families of pattern recognition receptors are responsible for detecting viral pathogens and generating innate immune responses. Non-self RNA appearing in a cell as a result of intracellular ...
  • Toll-like receptor signaling pathway, organism-specific biosystem (from KEGG)
    Toll-like receptor signaling pathway, organism-specific biosystemSpecific families of pattern recognition receptors are responsible for detecting microbial pathogens and generating innate immune responses. Toll-like receptors (TLRs) are membrane-bound receptors id...
  • Toll-like receptor signaling pathway, conserved biosystem (from KEGG)
    Toll-like receptor signaling pathway, conserved biosystemSpecific families of pattern recognition receptors are responsible for detecting microbial pathogens and generating innate immune responses. Toll-like receptors (TLRs) are membrane-bound receptors id...

General gene information

Homology

General protein information

Preferred Names
interleukin-12 subunit beta
Names
IL-12 p40 subunit
interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
interleukin-12 beta chain
interleukin-12 p40 subunit
interleukin-12p40

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_213571.1NP_998736.1  interleukin-12 subunit beta precursor

    See identical proteins and their annotated locations for NP_998736.1

    Status: PROVISIONAL

    Source sequence(s)
    AY262752
    UniProtKB/TrEMBL
    Q6X0K9
    Conserved Domains (1) summary
    pfam10420
    Location:125209
    IL12p40_C; Cytokine interleukin-12p40 C-terminus

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCg6a Primary Assembly

Genomic

  1. NC_006100.5 Reference GRCg6a Primary Assembly

    Range
    8854550..8879511
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025154822.1XP_025010590.1  interleukin-12 subunit beta isoform X1

    Conserved Domains (1) summary
    pfam10420
    Location:125209
    IL12p40_C; Cytokine interleukin-12p40 C-terminus
  2. XM_015293642.2XP_015149128.1  interleukin-12 subunit beta isoform X2

    UniProtKB/TrEMBL
    Q6X0K9
    Conserved Domains (1) summary
    pfam10420
    Location:125209
    IL12p40_C; Cytokine interleukin-12p40 C-terminus
  3. XM_015293641.2XP_015149127.1  interleukin-12 subunit beta isoform X1

    UniProtKB/TrEMBL
    Q6X0K9
    Related
    ENSGALP00000002143.5, ENSGALT00000002145.6
    Conserved Domains (1) summary
    pfam10420
    Location:125209
    IL12p40_C; Cytokine interleukin-12p40 C-terminus
Support Center