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gja9b gap junction protein alpha 9b [ Danio rerio (zebrafish) ]

Gene ID: 404625, updated on 9-Sep-2025
Official Symbol
gja9bprovided by ZNC
Official Full Name
gap junction protein alpha 9bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-2421
See related
Ensembl:ENSDARG00000086453 AllianceGenome:ZFIN:ZDB-GENE-040426-2421
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
cx52.9; zgc:77400
Summary
Predicted to enable gap junction channel activity. Predicted to be involved in cell-cell signaling. Predicted to act upstream of or within cell communication. Predicted to be located in gap junction and plasma membrane. Predicted to be part of connexin complex. Is expressed in several structures, including central nervous system; heart; kidney; liver; and retina. Orthologous to human GJA9 (gap junction protein alpha 9). [provided by Alliance of Genome Resources, Apr 2025]
Orthologs
all
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See gja9b in Genome Data Viewer
Location:
chromosome: 19
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2025_04 current GRCz12tu (GCF_049306965.1) 19 NC_133194.1 (37040..39220, complement)
RS_2024_08 previous assembly GRCz11 (GCF_000002035.6) 17 NC_007128.7 (53433992..53447683)

Chromosome 19 - NC_133194.1Genomic Context describing neighboring genes Neighboring gene MYC binding protein Neighboring gene serine and arginine rich splicing factor 10b Neighboring gene fatty acid binding protein 10b, liver basic

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Specific connectivity between photoreceptors and horizontal cells in the zebrafish retina. Klaassen LJ, et al. J Neurophysiol, 2016 Dec 1. PMID 27707811, Free PMC Article
  2. Synaptic transmission from horizontal cells to cones is impaired by loss of connexin hemichannels. Klaassen LJ, et al. PLoS Biol, 2011 Jul. PMID 21811399, Free PMC Article
  3. Complexity of gap junctions between horizontal cells of the carp retina. Greb H, et al. Neuroscience, 2017 Jan 6. PMID 27793781
  4. Hippocampal-like circuitry in the pallium of an electric fish: Possible substrates for recursive pattern separation and completion. Elliott SB, et al. J Comp Neurol, 2017 Jan 1. PMID 27292574
  5. Molecular diversity of connexin and pannexin genes in the retina of the zebrafish Danio rerio. Zoidl G, et al. Cell Commun Adhes, 2008 May. PMID 18649188

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. This study showed that Cx52.9 promoter activity occurred only in horizontal 1 cells.
    Title: Specific connectivity between photoreceptors and horizontal cells in the zebrafish retina.
Submit: New GeneRIF Correction

Homology

Clone Names

  • MGC77400

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables gap junction channel activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cell communication IEA
Inferred from Electronic Annotation
more info
  
involved_in cell-cell signaling IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in anchoring junction IEA
Inferred from Electronic Annotation
more info
  
part_of connexin complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of connexin complex IEA
Inferred from Electronic Annotation
more info
  
located_in gap junction IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
gap junction protein alpha 9b
Names
connexin 52.9

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_207093.1 → NP_996976.1  gap junction protein alpha 9b

    See identical proteins and their annotated locations for NP_996976.1

    Status: PROVISIONAL

    Source sequence(s)
    BC066457
    UniProtKB/TrEMBL
    A0A8M1PF58, Q6NYU5
    Related
    ENSDARP00000112133.1, ENSDART00000126630.3
    Conserved Domains (3) summary
    smart00037
    Location:44 → 76
    CNX; Connexin homologues
    smart01089
    Location:167 → 222
    Connexin_CCC; Gap junction channel protein cysteine-rich domain
    pfam00029
    Location:3 → 222
    Connexin; Connexin

RefSeqs of Annotated Genomes: GCF_049306965.1-RS_2025_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz12tu Primary Assembly

Genomic

  1. NC_133194.1 Reference GRCz12tu Primary Assembly

    Range
    37040..39220 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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