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CG7148 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 40432, updated on 4-Jan-2025

Summary

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Official Symbol
CG7148provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0046301
Locus tag
Dmel_CG7148
See related
AllianceGenome:FB:FBgn0046301
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BEST:GH10766; Dmel\CG7148; FBXL12
Summary
Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be part of SCF ubiquitin ligase complex. Predicted to be active in cytosol and nucleus. Is expressed in organism. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG7148 in Genome Data Viewer
Location:
78F4-78F4; 3-47 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (21830544..21832253, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (21823644..21825353, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene pseudo Neighboring gene Nopp140 Neighboring gene delta-1-Pyrroline-5-carboxylate dehydrogenase 1 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. F-box proteins: the key to protein degradation. Ho MS, et al. J Biomed Sci, 2006 Mar. PMID 16463014
  2. A systematic phenotypic screen of F-box genes through a tissue-specific RNAi-based approach in Drosophila. Dui W, et al. J Genet Genomics, 2012 Aug 20. PMID 22884096
  3. Defining components of the ß-catenin destruction complex and exploring its regulation and mechanisms of action during development. Roberts DM, et al. PLoS One, 2012. PMID 22359584, Free PMC Article
  4. Control of protein degradation by E3 ubiquitin ligases in Drosophila eye development. Ou CY, et al. Trends Genet, 2003 Jul. PMID 12850443
  5. A Drosophila protein-interaction map centered on cell-cycle regulators. Stanyon CA, et al. Genome Biol, 2004. PMID 15575970, Free PMC Article

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ISM
Inferred from Sequence Model
more info
  
Component Evidence Code Pubs
part_of SCF ubiquitin ligase complex ISM
Inferred from Sequence Model
more info
  
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG7148-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    21830544..21832253 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_141109.2 → NP_649366.1  uncharacterized protein Dmel_CG7148 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_649366.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VNX7
    Related
    FBpp0078102
    Conserved Domains (1) summary
    sd00034
    Location:333 → 358
    LRR_AMN1; leucine-rich repeat [structural motif]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VNX7 Q9VNX7

Gene LinkOut

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