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CUEDC1 CUE domain containing 1 [ Homo sapiens (human) ]

Gene ID: 404093, updated on 7-Jun-2020

Summary

Official Symbol
CUEDC1provided by HGNC
Official Full Name
CUE domain containing 1provided by HGNC
Primary source
HGNC:HGNC:31350
See related
Ensembl:ENSG00000180891
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in prostate (RPKM 6.5), brain (RPKM 6.5) and 25 other tissues See more
Orthologs

Genomic context

See CUEDC1 in Genome Data Viewer
Location:
17q22
Exon count:
14
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 17 NC_000017.11 (57861243..57955412, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (55938604..56032684, complement)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene RN7SK pseudogene 94 Neighboring gene mitochondrial ribosomal protein S23 Neighboring gene uncharacterized LOC107985065 Neighboring gene uncharacterized LOC101929185 Neighboring gene vascular endothelial zinc finger 1 Neighboring gene serine and arginine rich splicing factor 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Phenotypes

NHGRI GWAS Catalog

Description
Genetic variation influences glutamate concentrations in brains of patients with multiple sclerosis.
NHGRI GWA Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ20739, DKFZp547L163

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 

General protein information

Preferred Names
CUE domain-containing protein 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001271875.2NP_001258804.1  CUE domain-containing protein 1

    See identical proteins and their annotated locations for NP_001258804.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) differs in the 5' UTR, compared to variant 2. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC015813, AC015845, AK000746, BC056882, BG475111, BU732837
    Consensus CDS
    CCDS11599.1
    UniProtKB/Swiss-Prot
    Q9NWM3
    Related
    ENSP00000462717.1, ENST00000577830.6
    Conserved Domains (1) summary
    cd14366
    Location:4687
    CUE_CUED1; CUE domain found in CUE domain-containing protein 1 (CUED1) and similar proteins
  2. NM_001292025.1NP_001278954.1  CUE domain-containing protein 1

    See identical proteins and their annotated locations for NP_001278954.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) represents the longer transcript. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC015845, AK000746, BC056882, BU732837, CR627470
    Consensus CDS
    CCDS11599.1
    UniProtKB/Swiss-Prot
    Q9NWM3
    UniProtKB/TrEMBL
    Q6AHX0
    Related
    ENSP00000353373.2, ENST00000360238.6
    Conserved Domains (1) summary
    cd14366
    Location:4687
    CUE_CUED1; CUE domain found in CUE domain-containing protein 1 (CUED1) and similar proteins

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p13 Primary Assembly

    Range
    57861243..57955412 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017024640.2XP_016880129.1  CUE domain-containing protein 1 isoform X1

  2. XM_017024641.2XP_016880130.1  CUE domain-containing protein 1 isoform X2

  3. XM_011524812.2XP_011523114.1  CUE domain-containing protein 1 isoform X3

    Related
    ENSP00000463666.1, ENST00000577840.5

RNA

  1. XR_934459.3 RNA Sequence

  2. XR_001752509.2 RNA Sequence

  3. XR_934460.3 RNA Sequence

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