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VCAM1 vascular cell adhesion molecule 1 [ Canis lupus familiaris (dog) ]

Gene ID: 403982, updated on 27-Jun-2026
Official Symbol
VCAM1provided by VGNC
Official Full Name
vascular cell adhesion molecule 1provided by VGNC
Primary source
VGNC:VGNC:48240
See related
Ensembl:ENSCAFG00845012277 RGD:12102456
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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Try the new Transcripts and proteins table
See VCAM1 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
9
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 6 NC_051810.1 (49686812..49704968, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 6 NC_006588.4 (52013558..52031171, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 6 NC_049227.1 (49789615..49807229, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 6 NC_049266.1 (49380130..49397749, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 6 NC_049747.1 (49359940..49377559, complement)

Chromosome 6 - NC_051810.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111096514 Neighboring gene uncharacterized LOC119872253 Neighboring gene uncharacterized LOC119881528 Neighboring gene G protein-coupled receptor 88

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables integrin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
vascular cell adhesion protein 1
Names
V-CAM 1
VCAM-1

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001003298.1 → NP_001003298.1  vascular cell adhesion protein 1 precursor

    See identical proteins and their annotated locations for NP_001003298.1

    Status: PROVISIONAL

    Source sequence(s)
    U32086
    UniProtKB/Swiss-Prot
    Q28260
    UniProtKB/TrEMBL
    A0A8C0QZC8, A0A8I3NNW2
    Related
    ENSCAFP00845017196.1, ENSCAFT00845021861.1
    Conserved Domains (7) summary
    cd07689
    Location:404 → 502
    Ig2_VCAM-1; Second immunoglobulin (Ig)-like domain of vascular endothelial cell adhesion molecule-1 (VCAM-1, CD106) and intercellular cell adhesion molecule-1 (ICAM-1, CD54) and similar proteins
    smart00408
    Location:238 → 298
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:232 → 308
    IG_like; Immunoglobulin like
    pfam07679
    Location:26 → 112
    I-set; Immunoglobulin I-set domain
    pfam00047
    Location:318 → 385
    ig; Immunoglobulin domain
    pfam13927
    Location:606 → 672
    Ig_3; Immunoglobulin domain
    cl11960
    Location:30 → 98
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051810.1 Reference ROS_Cfam_1.0

    Range
    49686812..49704968 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038667558.1 → XP_038523486.1  vascular cell adhesion protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0QZC8, A0A8I3NNW2
    Conserved Domains (5) summary
    smart00408
    Location:247 → 307
    IGc2; Immunoglobulin C-2 Type
    smart00409
    Location:528 → 605
    IG; Immunoglobulin
    cd00096
    Location:322 → 327
    Ig; Ig strand A [structural motif]
    cd07689
    Location:413 → 513
    IgC2_VCAM-1; Immunoglobulin (Ig)-like domain of vascular endothelial cell adhesion molecule-1 (VCAM-1) and similar proteins; member of the C2-set of IgSF domains
    cl11960
    Location:322 → 410
    Ig; Immunoglobulin domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049266.1 Alternate UMICH_Zoey_3.1

    Range
    49380130..49397749 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049747.1 Alternate UNSW_CanFamBas_1.0

    Range
    49359940..49377559 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049227.1 Alternate UU_Cfam_GSD_1.0

    Range
    49789615..49807229 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006588.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    52013558..52031171 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q28260.1 GenPept UniProtKB/Swiss-Prot:Q28260

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Research Materials