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TfAP-2 Transcription factor AP-2 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 40398, updated on 28-Aug-2019

Summary

Official Symbol
TfAP-2provided by FlyBase
Official Full Name
Transcription factor AP-2provided by FlyBase
Primary source
FLYBASE:FBgn0261953
Locus tag
Dmel_CG7807
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
AP-2; AP-2alpha; CG7807; dAP-2; DAP-2; dAP-2alpha; Dmel\CG7807; dTfap2; l(3)1215

Genomic context

See TfAP-2 in Genome Data Viewer
Location:
78D8-78E1; 3-47 cM
Exon count:
10
Annotation release Status Assembly Chr Location
Release 6.26 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (21586828..21613349)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (21579928..21606449)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR43939 Neighboring gene hairpin RNA:CR46340 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR43940 Neighboring gene S1P Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
DNA-binding transcription factor activity IDA
Inferred from Direct Assay
more info
PubMed 
DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
RNA polymerase II regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
adult feeding behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
adult locomotory behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
imaginal disc-derived leg joint morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
imaginal disc-derived leg morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
imaginal disc-derived male genitalia development IMP
Inferred from Mutant Phenotype
more info
PubMed 
inter-male aggressive behavior IGI
Inferred from Genetic Interaction
more info
PubMed 
male courtship behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
PubMed 
proboscis development IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of circadian sleep/wake cycle, sleep IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
transcription factor AP-2
Names
AP-2
CG7807-PA
CG7807-PB
CG7807-PC
CG7807-PD
CG7807-PE
CG7807-PF
TfAP-2-PA
TfAP-2-PB
TfAP-2-PC
TfAP-2-PD
TfAP-2-PE
TfAP-2-PF
lethal (3) 1215
stummelbein

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    21586828..21613349
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001275251.1NP_001262180.1  transcription factor AP-2, isoform F [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001262180.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PFX8
    Related
    FBpp0305658, FBtr0333468
    Conserved Domains (1) summary
    pfam03299
    Location:239439
    TF_AP-2; Transcription factor AP-2
  2. NM_001275248.1NP_001262177.1  transcription factor AP-2, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001262177.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PG57
    Related
    FBpp0305655, FBtr0333465
    Conserved Domains (1) summary
    pfam03299
    Location:233433
    TF_AP-2; Transcription factor AP-2
  3. NM_001275249.1NP_001262178.1  transcription factor AP-2, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001262178.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PIH9
    Related
    FBpp0305656, FBtr0333466
    Conserved Domains (1) summary
    pfam03299
    Location:245445
    TF_AP-2; Transcription factor AP-2
  4. NM_141079.3NP_649336.1  transcription factor AP-2, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_649336.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O96378
    Related
    FBpp0078072, FBtr0078418
    Conserved Domains (1) summary
    pfam03299
    Location:239439
    TF_AP-2; Transcription factor AP-2
  5. NM_001275250.1NP_001262179.1  transcription factor AP-2, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001262179.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PD85
    Related
    FBpp0305657, FBtr0333467
    Conserved Domains (1) summary
    pfam03299
    Location:241441
    TF_AP-2; Transcription factor AP-2
  6. NM_168927.2NP_730664.1  transcription factor AP-2, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_730664.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O76923
    Related
    FBpp0078073, FBtr0078419
    Conserved Domains (1) summary
    pfam03299
    Location:235435
    TF_AP-2; Transcription factor AP-2
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