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TSHR thyroid stimulating hormone receptor [ Canis lupus familiaris (dog) ]

Gene ID: 403968, updated on 25-Jul-2026
Official Symbol
TSHRprovided by VGNC
Official Full Name
thyroid stimulating hormone receptorprovided by VGNC
Primary source
VGNC:VGNC:47902
See related
Ensembl:ENSCAFG00845008943 RGD:12311078
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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See TSHR in Genome Data Viewer
Location:
chromosome: 8
Exon count:
10
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 8 NC_051812.1 (53556926..53712913)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 8 NC_006590.4 (52885443..53041069)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 8 NC_049229.1 (53634852..53790765)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 8 NC_049268.1 (53238978..53394541)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 8 NC_049749.1 (53242681..53398330)

Chromosome 8 - NC_051812.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102153427 Neighboring gene centrosomal protein 128 Neighboring gene uncharacterized LOC111097123 Neighboring gene uncharacterized LOC111097124 Neighboring gene small nucleolar RNA SNORA79 Neighboring gene general transcription factor IIA subunit 1 Neighboring gene stonin 2 Neighboring gene uncharacterized LOC102153608

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Nucleotide sequence of the dog thyrotropin receptor cDNA. Parmentier M, et al. Nucleic Acids Res, 1989 Dec 25. PMID 2602159, Free PMC Article
  2. Molecular cloning of the thyrotropin receptor. Parmentier M, et al. Science, 1989 Dec 22. PMID 2556796
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables thyroid-stimulating hormone receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
thyrotropin receptor
Names
TSH-R

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001003285.1 → NP_001003285.1  thyrotropin receptor precursor

    See identical proteins and their annotated locations for NP_001003285.1

    Status: PROVISIONAL

    Source sequence(s)
    X17146
    UniProtKB/Swiss-Prot
    P14763
    UniProtKB/TrEMBL
    A0A8C0KZB7, A0A8I3MZT7
    Related
    ENSCAFP00845012299.1, ENSCAFT00845015812.1
    Conserved Domains (3) summary
    sd00033
    Location:78 → 102
    LRR_RI; leucine-rich repeat [structural motif]
    cd15964
    Location:415 → 689
    7tmA_TSH-R; thyroid-stimulating hormone receptor (or thyrotropin receptor), member of the class A family of seven-transmembrane G protein-coupled receptors
    cl26222
    Location:65 → 221
    LRR_5; Leucine rich repeats (6 copies)

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051812.1 Reference ROS_Cfam_1.0

    Range
    53556926..53712913
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038672857.1 → XP_038528785.1  thyrotropin receptor isoform X1

    UniProtKB/TrEMBL
    A0A8I3N6M6
    Conserved Domains (3) summary
    sd00033
    Location:78 → 102
    LRR_RI; leucine-rich repeat [structural motif]
    cd15964
    Location:390 → 664
    7tmA_TSH-R; thyroid-stimulating hormone receptor (or thyrotropin receptor), member of the class A family of seven-transmembrane G protein-coupled receptors
    pfam13306
    Location:65 → 196
    LRR_5; Leucine rich repeats (6 copies)

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049268.1 Alternate UMICH_Zoey_3.1

    Range
    53238978..53394541
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049749.1 Alternate UNSW_CanFamBas_1.0

    Range
    53242681..53398330
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049229.1 Alternate UU_Cfam_GSD_1.0

    Range
    53634852..53790765
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006590.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    52885443..53041069
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P14763.1 GenPept UniProtKB/Swiss-Prot:P14763

Gene LinkOut

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