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ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 [ Canis lupus familiaris (dog) ]

Gene ID: 403878, updated on 11-May-2017
Gene symbol
ATP2A2
Gene description
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2
See related
Ensembl:ENSCAFG00000008434
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
SERCA2A
Orthologs
Location:
chromosome: 26
Exon count:
21
Annotation release Status Assembly Chr Location
104 current CanFam3.1 (GCF_000002285.3) 26 NC_006608.3 (8148166..8209397)

Chromosome 26 - NC_006608.3Genomic Context describing neighboring genes Neighboring gene purinergic receptor P2X 7 Neighboring gene intraflagellar transport 81 Neighboring gene uncharacterized LOC102153400 Neighboring gene anaphase promoting complex subunit 7

Genomic Sequence:
NC_006608.3 Chromosome 26 Reference CanFam3.1 Primary Assembly

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
S100 protein binding IEA
Inferred from Electronic Annotation
more info
 
calcium ion binding IEA
Inferred from Electronic Annotation
more info
 
calcium-transporting ATPase activity IEA
Inferred from Electronic Annotation
more info
 
enzyme binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
ATP hydrolysis coupled cation transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
ER-nucleus signaling pathway IEA
Inferred from Electronic Annotation
more info
 
T-tubule organization IEA
Inferred from Electronic Annotation
more info
 
calcium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
calcium ion transport from cytosol to endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
cardiac muscle hypertrophy in response to stress IEA
Inferred from Electronic Annotation
more info
 
cellular response to oxidative stress IEA
Inferred from Electronic Annotation
more info
 
negative regulation of heart contraction IEA
Inferred from Electronic Annotation
more info
 
organelle organization IEA
Inferred from Electronic Annotation
more info
 
positive regulation of endoplasmic reticulum calcium ion concentration IEA
Inferred from Electronic Annotation
more info
 
regulation of calcium ion-dependent exocytosis of neurotransmitter IEA
Inferred from Electronic Annotation
more info
 
regulation of the force of heart contraction IEA
Inferred from Electronic Annotation
more info
 
sarcoplasmic reticulum calcium ion transport IEA
Inferred from Electronic Annotation
more info
 
transition between fast and slow fiber IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
nucleoplasm IEA
Inferred from Electronic Annotation
more info
 
ribbon synapse IEA
Inferred from Electronic Annotation
more info
 
sarcoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
sarcoplasmic/endoplasmic reticulum calcium ATPase 2
Names
SERCA2
SR Ca(2+)-ATPase 2
calcium ATPase
calcium pump 2
calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform
endoplasmic reticulum class 1/2 Ca(2+) ATPase
sarcoplasmic reticulum Ca2+-transport ATPase isoform
NP_001003214.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001003214.1NP_001003214.1  sarcoplasmic/endoplasmic reticulum calcium ATPase 2

    See identical proteins and their annotated locations for NP_001003214.1

    Status: PROVISIONAL

    Source sequence(s)
    U94345
    UniProtKB/Swiss-Prot
    O46674
    UniProtKB/TrEMBL
    B6CAN1
    Related
    ENSCAFP00000025477.3, ENSCAFT00000027396.3
    Conserved Domains (6) summary
    TIGR01116
    Location:53988
    ATPase-IIA1_Ca; sarco/endoplasmic reticulum calcium-translocating P-type ATPase
    pfam00122
    Location:93340
    E1-E2_ATPase; E1-E2 ATPase
    pfam00689
    Location:783986
    Cation_ATPase_C; Cation transporting ATPase, C-terminus
    pfam00690
    Location:472
    Cation_ATPase_N; Cation transporter/ATPase, N-terminus
    pfam12710
    Location:605711
    HAD; haloacid dehalogenase-like hydrolase
    pfam13246
    Location:419527
    Cation_ATPase; Cation transport ATPase (P-type)

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CanFam3.1 Primary Assembly

Genomic

  1. NC_006608.3 Reference CanFam3.1 Primary Assembly

    Range
    8148166..8209397
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_295678.2 RNA Sequence

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