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MS4A2 membrane spanning 4-domains A2 [ Canis lupus familiaris (dog) ]

Gene ID: 403799, updated on 25-Jul-2026
Official Symbol
MS4A2provided by VGNC
Official Full Name
membrane spanning 4-domains A2provided by VGNC
Primary source
VGNC:VGNC:43432
See related
Ensembl:ENSCAFG00845019696 RGD:12259815
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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See MS4A2 in Genome Data Viewer
Location:
chromosome: 21
Exon count:
9
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 21 NC_051825.1 (51612389..51629878)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 21 NC_006603.4 (49890835..49897600)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 21 NC_049242.1 (51392625..51399386)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 21 NC_049281.1 (50670449..50677218)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 21 NC_049762.1 (50767877..50774639)

Chromosome 21 - NC_051825.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119865040 Neighboring gene transcobalamin 1 Neighboring gene uncharacterized LOC111091593 Neighboring gene uncharacterized LOC111091592 Neighboring gene uncharacterized LOC102155706 Neighboring gene membrane-spanning 4-domains subfamily A member 4A-like Neighboring gene membrane-spanning 4-domains subfamily A member 3-like

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Molecular cloning of cDNAs encoding dog high-affinity IgE receptor alpha, beta, and gamma chains. Goitsuka R, et al. Immunogenetics, 1999 Jun. PMID 10380708
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of Fc-epsilon receptor I complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
high affinity immunoglobulin epsilon receptor subunit beta
Names
high-affinity IgE receptor beta-chain
membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001003172.3 → NP_001003172.3  high affinity immunoglobulin epsilon receptor subunit beta

    Status: VALIDATED

    Source sequence(s)
    JAAUVH010000057
    UniProtKB/TrEMBL
    A0A8I3PFF6
    Related
    ENSCAFP00845027206.1, ENSCAFT00845034738.1
    Conserved Domains (1) summary
    pfam04103
    Location:60 → 202
    CD20; CD20-like family

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051825.1 Reference ROS_Cfam_1.0

    Range
    51612389..51629878
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038429448.1 → XP_038285376.1  high affinity immunoglobulin epsilon receptor subunit beta isoform X1

    UniProtKB/TrEMBL
    A0A8I3PFF6
    Conserved Domains (1) summary
    pfam04103
    Location:60 → 202
    CD20; CD20-like family

  2. XM_038429453.1 → XP_038285381.1  high affinity immunoglobulin epsilon receptor subunit beta isoform X1

    UniProtKB/TrEMBL
    A0A8I3PFF6
    Conserved Domains (1) summary
    pfam04103
    Location:60 → 202
    CD20; CD20-like family

  3. XM_038429454.1 → XP_038285382.1  high affinity immunoglobulin epsilon receptor subunit beta isoform X2

    Conserved Domains (1) summary
    pfam04103
    Location:55 → 197
    CD20; CD20-like family

  4. XM_038429452.1 → XP_038285380.1  high affinity immunoglobulin epsilon receptor subunit beta isoform X1

    UniProtKB/TrEMBL
    A0A8I3PFF6
    Conserved Domains (1) summary
    pfam04103
    Location:60 → 202
    CD20; CD20-like family

  5. XM_038429451.1 → XP_038285379.1  high affinity immunoglobulin epsilon receptor subunit beta isoform X1

    UniProtKB/TrEMBL
    A0A8I3PFF6
    Conserved Domains (1) summary
    pfam04103
    Location:60 → 202
    CD20; CD20-like family

  6. XM_038429450.1 → XP_038285378.1  high affinity immunoglobulin epsilon receptor subunit beta isoform X1

    UniProtKB/TrEMBL
    A0A8I3PFF6
    Conserved Domains (1) summary
    pfam04103
    Location:60 → 202
    CD20; CD20-like family

  7. XM_038429449.1 → XP_038285377.1  high affinity immunoglobulin epsilon receptor subunit beta isoform X1

    UniProtKB/TrEMBL
    A0A8I3PFF6
    Conserved Domains (1) summary
    pfam04103
    Location:60 → 202
    CD20; CD20-like family

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049281.1 Alternate UMICH_Zoey_3.1

    Range
    50670449..50677218
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049762.1 Alternate UNSW_CanFamBas_1.0

    Range
    50767877..50774639
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049242.1 Alternate UU_Cfam_GSD_1.0

    Range
    51392625..51399386
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006603.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    49890835..49897600
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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