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HTR1B 5-hydroxytryptamine receptor 1B [ Canis lupus familiaris (dog) ]

Gene ID: 403741, updated on 18-Sep-2018

Summary

Gene symbol
HTR1B
Gene description
5-hydroxytryptamine receptor 1B
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Annotation information
Annotation category: partial on reference assembly
Orthologs

Genomic context

See HTR1B in Genome Data Viewer
Location:
chromosome: 12
Exon count:
1
Annotation release Status Assembly Chr Location
105 current CanFam3.1 (GCF_000002285.3) 12 NC_006594.3 (38659088..38659546, complement)

Chromosome 12 - NC_006594.3Genomic Context describing neighboring genes Neighboring gene 60S acidic ribosomal protein P0 pseudogene Neighboring gene nucleolar protein of 40 kDa pseudogene Neighboring gene uncharacterized LOC111098172 Neighboring gene ATPase ASNA1 pseudogene Neighboring gene meiotic double-stranded break formation protein 4

Genomic regions, transcripts, and products

Genomic Sequence:
NC_006594.3 Chromosome 12 Reference CanFam3.1 Primary Assembly

Pathways from BioSystems

  • Neuroactive ligand-receptor interaction, organism-specific biosystem (from KEGG)
    Neuroactive ligand-receptor interaction, organism-specific biosystem
    Neuroactive ligand-receptor interaction
  • Neuroactive ligand-receptor interaction, conserved biosystem (from KEGG)
    Neuroactive ligand-receptor interaction, conserved biosystem
    Neuroactive ligand-receptor interaction
  • Serotonergic synapse, organism-specific biosystem (from KEGG)
    Serotonergic synapse, organism-specific biosystemSerotonin (5-Hydroxytryptamine, 5-HT) is a monoamine neurotransmitter that plays important roles in physiological functions such as learning and memory, emotion, sleep, pain, motor function and endoc...
  • Taste transduction, organism-specific biosystem (from KEGG)
    Taste transduction, organism-specific biosystemFive basic tastes are recognized by humans and most other animals - bitter, sweet, sour, salty and umami. In vertebrates, taste stimuli are detected by taste receptor cells (TRCs). At least three dis...
  • Taste transduction, conserved biosystem (from KEGG)
    Taste transduction, conserved biosystemFive basic tastes are recognized by humans and most other animals - bitter, sweet, sour, salty and umami. In vertebrates, taste stimuli are detected by taste receptor cells (TRCs). At least three dis...
  • cAMP signaling pathway, organism-specific biosystem (from KEGG)
    cAMP signaling pathway, organism-specific biosystemcAMP is one of the most common and universal second messengers, and its formation is promoted by adenylyl cyclase (AC) activation after ligation of G protein-coupled receptors (GPCRs) by ligands incl...
  • cAMP signaling pathway, conserved biosystem (from KEGG)
    cAMP signaling pathway, conserved biosystemcAMP is one of the most common and universal second messengers, and its formation is promoted by adenylyl cyclase (AC) activation after ligation of G protein-coupled receptors (GPCRs) by ligands incl...

General gene information

Markers

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
G protein-coupled serotonin receptor activity ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
adenylate cyclase-inhibiting serotonin receptor signaling pathway ISS
Inferred from Sequence or Structural Similarity
more info
 
behavior IEA
Inferred from Electronic Annotation
more info
 
bone remodeling IEA
Inferred from Electronic Annotation
more info
 
cellular response to alkaloid ISS
Inferred from Sequence or Structural Similarity
more info
 
cellular response to drug ISS
Inferred from Sequence or Structural Similarity
more info
 
chemical synaptic transmission IEA
Inferred from Electronic Annotation
more info
 
negative regulation of serotonin secretion ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of behavior IEA
Inferred from Electronic Annotation
more info
 
vasoconstriction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
integral component of plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
5-hydroxytryptamine receptor 1B
Names
5-HT-1B
5-HT1B
5-HT1D beta
5-HT1D subtype beta
5-HTR1B
5-Hydroxytryptamine 1D receptor subtype beta
serotonin receptor 1B

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001006948.1NP_001006949.1  5-hydroxytryptamine receptor 1B

    See identical proteins and their annotated locations for NP_001006949.1

    Status: PROVISIONAL

    Source sequence(s)
    AB193090
    UniProtKB/Swiss-Prot
    P79250
    Conserved Domains (2) summary
    pfam00001
    Location:66368
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:63185
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CanFam3.1 Primary Assembly

Genomic

  1. NC_006594.3 Reference CanFam3.1 Primary Assembly

    Range
    38659088..38659546 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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