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TBXT T-box transcription factor T [ Canis lupus familiaris (dog) ]

Gene ID: 403653, updated on 1-Mar-2025
Official Symbol
TBXTprovided by VGNC
Official Full Name
T-box transcription factor Tprovided by VGNC
Primary source
VGNC:VGNC:47058
See related
Ensembl:ENSCAFG00845004679 RGD:12372074
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
T; brachyury
Orthologs
all
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Try the new Transcripts and proteins table
See TBXT in Genome Data Viewer
Location:
chromosome: 1
Exon count:
8
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 1 NC_051805.1 (54360266..54369833, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 1 NC_006583.4 (54970966..54979790, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 1 NC_049222.1 (54733858..54742687, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 1 NC_049261.1 (54257349..54266189, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 1 NC_049742.1 (54107519..54116264, complement)

Chromosome 1 - NC_051805.1Genomic Context describing neighboring genes Neighboring gene phosphodiesterase 10A Neighboring gene uncharacterized LOC102152011 Neighboring gene glutathione S-transferase kappa 1-like Neighboring gene U1 spliceosomal RNA Neighboring gene proline rich 18

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Canine homolog of the T-box transcription factor T; failure of the protein to bind to its DNA target leads to a short-tail phenotype. Haworth K, et al. Mamm Genome, 2001 Mar. PMID 11252170
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell fate specification IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in heart morphogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mesoderm formation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in somitogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
T-box transcription factor T
Names
T brachyury protein
T brachyury transcription factor
T, brachyury homolog
brachyury protein
protein T

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001003092.1 → NP_001003092.1  T-box transcription factor T

    See identical proteins and their annotated locations for NP_001003092.1

    Status: PROVISIONAL

    Source sequence(s)
    AJ245513
    UniProtKB/Swiss-Prot
    Q9GL27
    UniProtKB/TrEMBL
    A0A8C0L3P5
    Related
    ENSCAFP00845006603.1, ENSCAFT00845008391.1
    Conserved Domains (1) summary
    cd20192
    Location:42 → 219
    T-box_TBXT_TBX19-like; DNA-binding domain of T-box transcription factor T, T-box transcription factor 19 and related T-box proteins

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051805.1 Reference ROS_Cfam_1.0

    Range
    54360266..54369833 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038653377.1 → XP_038509305.1  T-box transcription factor T isoform X1

    UniProtKB/TrEMBL
    A0A8C0RFC1, A0A8I3MTQ9
    Related
    ENSCAFP00845006600.1, ENSCAFT00845008388.1
    Conserved Domains (1) summary
    cd20192
    Location:42 → 219
    T-box_TBXT_TBX19-like; DNA-binding domain of T-box transcription factor T, T-box transcription factor 19 and related T-box proteins

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049261.1 Alternate UMICH_Zoey_3.1

    Range
    54257349..54266189 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049742.1 Alternate UNSW_CanFamBas_1.0

    Range
    54107519..54116264 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049222.1 Alternate UU_Cfam_GSD_1.0

    Range
    54733858..54742687 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006583.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    54970966..54979790 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9GL27.1 GenPept UniProtKB/Swiss-Prot:Q9GL27

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials