TBXT T-box transcription factor T [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: TBXTprovided by VGNC
Official Full Name: T-box transcription factor Tprovided by VGNC
Primary source: VGNC:VGNC:47058
See related: Ensembl:ENSCAFG00845004679
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as: T; brachyury
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	1	NC_051805.1 (54360266..54369833, complement)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	1	NC_006583.4 (54970966..54979790, complement)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	1	NC_049222.1 (54733858..54742687, complement)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	1	NC_049261.1 (54257349..54266189, complement)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	1	NC_049742.1 (54107519..54116264, complement)

Chromosome 1 - NC_051805.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info	PubMed
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cell fate specification	IEA Inferred from Electronic Annotation more info	PubMed
involved_in heart morphogenesis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in mesoderm formation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed
involved_in somitogenesis	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: T-box transcription factor T

Names: T brachyury protein; T brachyury transcription factor; T, brachyury homolog; brachyury protein; protein T

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001003092.1 → NP_001003092.1 T-box transcription factor T

See identical proteins and their annotated locations for NP_001003092.1

Status: PROVISIONAL

Source sequence(s)

AJ245513

UniProtKB/Swiss-Prot

Q9GL27

UniProtKB/TrEMBL

A0A8C0L3P5

Related

ENSCAFP00845006603.1, ENSCAFT00845008391.1

Conserved Domains (1) summary

cd20192
Location:42 → 219

T-box_TBXT_TBX19-like; DNA-binding domain of T-box transcription factor T, T-box transcription factor 19 and related T-box proteins

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051805.1 Reference ROS_Cfam_1.0

Range

54360266..54369833 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038653377.1 → XP_038509305.1 T-box transcription factor T isoform X1

UniProtKB/TrEMBL

A0A8C0RFC1, A0A8I3MTQ9

Related

ENSCAFP00845006600.1, ENSCAFT00845008388.1

Conserved Domains (1) summary

cd20192
Location:42 → 219

T-box_TBXT_TBX19-like; DNA-binding domain of T-box transcription factor T, T-box transcription factor 19 and related T-box proteins