HSPB8 heat shock protein family B (small) member 8 [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: HSPB8provided by VGNC
Official Full Name: heat shock protein family B (small) member 8provided by VGNC
Primary source: VGNC:VGNC:52935
See related: RGD:12237880
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Canis lupus familiaris
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: all
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Genomic context

Location:: chromosome: 26

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	26	NC_051830.1 (15606043..15618322)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	26	NC_006608.4 (15343116..15355393)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	26	NC_049247.1 (15685151..15697445)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	26	NC_049286.1 (15575862..15588132)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	26	NC_049767.1 (15643221..15655514)

Chromosome 26 - NC_051830.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables protein homodimerization activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cellular response to unfolded protein	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed
part_of protein folding chaperone complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: heat shock protein beta-8

Names: H11 kinase; heat shock 27kDa protein 8; protein kinase H11

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001003029.1 → NP_001003029.1 heat shock protein beta-8

See identical proteins and their annotated locations for NP_001003029.1

Status: PROVISIONAL

Source sequence(s)

AF525493

UniProtKB/Swiss-Prot

Q8MJ36

UniProtKB/TrEMBL

A0A8I3PXI8

Conserved Domains (2) summary

cd06480
Location:80 → 170

ACD_HspB8_like; Alpha-crystallin domain (ACD) found in mammalian 21.6 KDa small heat shock protein (sHsp) HspB8, also denoted as Hsp22 in humans, and similar proteins. sHsps are molecular chaperones that suppress protein aggregation and protect against cell stress, and ...

COG0071
Location:105 → 173

IbpA; Molecular chaperone IbpA, HSP20 family [Posttranslational modification, protein turnover, chaperones]