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SREBF1 sterol regulatory element binding transcription factor 1 [ Canis lupus familiaris (dog) ]

Gene ID: 403475, updated on 18-Sep-2020

Summary

Official Symbol
SREBF1provided by VGNC
Official Full Name
sterol regulatory element binding transcription factor 1provided by VGNC
Primary source
VGNC:VGNC:46795
See related
Ensembl:ENSCAFG00000018436
Gene type
protein coding
RefSeq status
INFERRED
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
SREBP1
Orthologs

Genomic context

See SREBF1 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
20
Annotation release Status Assembly Chr Location
105 current CanFam3.1 (GCF_000002285.3) 5 NC_006587.3 (41663809..41686764)

Chromosome 5 - NC_006587.3Genomic Context describing neighboring genes Neighboring gene dynein regulatory complex subunit 3 Neighboring gene target of myb1 like 2 membrane trafficking protein Neighboring gene ribosomal protein L37 pseudogene Neighboring gene microRNA mir-33b Neighboring gene retinoic acid induced 1 Neighboring gene uncharacterized LOC111095910 Neighboring gene phosphatidylethanolamine N-methyltransferase

Genomic regions, transcripts, and products

Genomic Sequence:
NC_006587.3 Chromosome 5 Reference CanFam3.1 Primary Assembly

Pathways from PubChem

General gene information

Markers

Homology

General protein information

Preferred Names
sterol regulatory element-binding protein 1
Names
sterol regulatory element binding-protein 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001197083.1NP_001184012.1  sterol regulatory element-binding protein 1

    Status: INFERRED

    Source sequence(s)
    AAEX03003724
    UniProtKB/TrEMBL
    J9NSD3
    Conserved Domains (1) summary
    cd00083
    Location:355412
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CanFam3.1 Primary Assembly

Genomic

  1. NC_006587.3 Reference CanFam3.1 Primary Assembly

    Range
    41663809..41686764
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_014113166.2XP_013968641.1  sterol regulatory element-binding protein 1 isoform X1

    Related
    ENSCAFP00000027222.4, ENSCAFT00000029276.4
    Conserved Domains (2) summary
    cd00083
    Location:322379
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    cl26464
    Location:48282
    Atrophin-1; Atrophin-1 family
  2. XM_014113167.2XP_013968642.1  sterol regulatory element-binding protein 1 isoform X3

    Conserved Domains (2) summary
    cd00083
    Location:355412
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    cl26464
    Location:81315
    Atrophin-1; Atrophin-1 family
  3. XM_022418000.1XP_022273708.1  sterol regulatory element-binding protein 1 isoform X2

    Related
    ENSCAFP00000037612.2, ENSCAFT00000043059.3
    Conserved Domains (2) summary
    cd00083
    Location:298355
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    cl26464
    Location:24258
    Atrophin-1; Atrophin-1 family
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