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ABCC1 ATP binding cassette subfamily C member 1 [ Canis lupus familiaris (dog) ]

Gene ID: 403453, updated on 17-Nov-2020

Summary

Official Symbol
ABCC1provided by VGNC
Official Full Name
ATP binding cassette subfamily C member 1provided by VGNC
Primary source
VGNC:VGNC:54275
See related
Ensembl:ENSCAFG00000018208
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
MRP1
Annotation information
Annotation category: suggests misassembly
Annotation category: partial on reference assembly
Orthologs

Genomic context

See ABCC1 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
30
Annotation release Status Assembly Chr Location
105 current CanFam3.1 (GCF_000002285.3) 6 NC_006588.3 (27855702..27950140, complement)

Chromosome 6 - NC_006588.3Genomic Context describing neighboring genes Neighboring gene nodal modulator 1 Neighboring gene ATP binding cassette subfamily C member 6 Neighboring gene uncharacterized LOC111096296 Neighboring gene centrosomal protein 20 Neighboring gene myosin heavy chain 11 Neighboring gene nudE neurodevelopment protein 1

Genomic regions, transcripts, and products

Genomic Sequence:
NC_006588.3 Chromosome 6 Reference CanFam3.1 Primary Assembly

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

General gene information

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
ABC-type transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
 
ATP binding IEA
Inferred from Electronic Annotation
more info
 
ATPase activity IEA
Inferred from Electronic Annotation
more info
 
ATPase-coupled glutathione S-conjugate transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
 
ATPase-coupled xenobiotic transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
xenobiotic transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
leukotriene transport ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of inflammatory response ISS
Inferred from Sequence or Structural Similarity
more info
 
response to drug ISS
Inferred from Sequence or Structural Similarity
more info
 
transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
xenobiotic transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
multidrug resistance-associated protein 1
Names
ATP-binding cassette sub-family C member 1
LTC4 transporter
glutathione-S-conjugate-translocating ATPase ABCC1
leukotriene C(4) transporter
multidrug resistance protein 1
NP_001002971.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001002971.1NP_001002971.1  multidrug resistance-associated protein 1

    See identical proteins and their annotated locations for NP_001002971.1

    Status: PROVISIONAL

    Source sequence(s)
    AY363728
    UniProtKB/Swiss-Prot
    Q6UR05
    Related
    ENSCAFP00000026911.4, ENSCAFT00000028933.5
    Conserved Domains (1) summary
    TIGR00957
    Location:71530
    MRP_assoc_pro; multi drug resistance-associated protein (MRP)

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CanFam3.1 Primary Assembly

Genomic

  1. NC_006588.3 Reference CanFam3.1 Primary Assembly

    Range
    27855702..27950140 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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