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gps2.L G protein pathway suppressor 2 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 403370, updated on 5-Sep-2025
Official Symbol
gps2.L
Official Full Name
G protein pathway suppressor 2 L homeolog
Primary source
Xenbase:XB-GENE-486869
Locus tag
XELAEV_18019674mg
See related
EnsemblRapid:ENSXLAG00005022448 AllianceGenome:Xenbase:XB-GENE-486869
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
gps2; gps2.S
Summary
Orthologous to human GPS2 (G protein pathway suppressor 2). [provided by Alliance of Genome Resources, Jul 2025]
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See gps2.L in Genome Data Viewer
Location:
chromosome: 3L
Exon count:
12
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 3L NC_054375.1 (161152750..161179817, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 3L NC_030728.1 (144005910..144019192, complement)

Chromosome 3L - NC_054375.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 2 (facilitated glucose transporter), member 4 L homeolog Neighboring gene Y-box binding protein 2 L homeolog Neighboring gene solute carrier family 16 member 13 L homeolog Neighboring gene tumor protein p53 L homeolog

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Involvement of corepressor complex subunit GPS2 in transcriptional pathways governing human bile acid biosynthesis. Sanyal S, et al. Proc Natl Acad Sci U S A, 2007 Oct 2. PMID 17895379, Free PMC Article
  2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Preferred Names
G protein pathway suppressor 2 L homeolog
Names
G protein pathway suppressor 2 S homeolog

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001090946.1 → NP_001084415.1  G protein pathway suppressor 2 L homeolog

    See identical proteins and their annotated locations for NP_001084415.1

    Status: PROVISIONAL

    Source sequence(s)
    BC097591
    UniProtKB/TrEMBL
    Q4QR41, Q6XM89
    Related
    ENSXLAP00005066011.1, ENSXLAT00005067534.1
    Conserved Domains (2) summary
    pfam15991
    Location:5 → 290
    G_path_suppress; G-protein pathway suppressor
    cl20817
    Location:40 → 105
    GBP_C; Guanylate-binding protein, C-terminal domain

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054375.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    161152750..161179817 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041585036.1 → XP_041440970.1  G protein pathway suppressor 2 L homeolog isoform X3

    UniProtKB/TrEMBL
    A0A8J1MIU0, Q6XM89
    Conserved Domains (1) summary
    COG1196
    Location:38 → 113
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  2. XM_041585035.1 → XP_041440969.1  G protein pathway suppressor 2 L homeolog isoform X2

    UniProtKB/TrEMBL
    A0A8J1MGX4, Q6XM89
    Related
    ENSXLAP00005066030.1, ENSXLAT00005067553.1
    Conserved Domains (1) summary
    COG1196
    Location:38 → 113
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  3. XM_041585034.1 → XP_041440968.1  G protein pathway suppressor 2 L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A8J1MHH0, Q6XM89
    Related
    ENSXLAP00005066069.1, ENSXLAT00005067592.1
    Conserved Domains (1) summary
    COG1196
    Location:38 → 113
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
Nucleotide Protein Strain
Heading Accession and Version

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