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ZBTB34 zinc finger and BTB domain containing 34 [ Homo sapiens (human) ]

Gene ID: 403341, updated on 27-Aug-2021

Summary

Official Symbol
ZBTB34provided by HGNC
Official Full Name
zinc finger and BTB domain containing 34provided by HGNC
Primary source
HGNC:HGNC:31446
See related
Ensembl:ENSG00000177125 MIM:611692
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ZNF918
Expression
Ubiquitous expression in bone marrow (RPKM 6.2), placenta (RPKM 3.9) and 25 other tissues See more
Orthologs
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Genomic context

See ZBTB34 in Genome Data Viewer
Location:
9q33.3
Exon count:
4
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 9 NC_000009.12 (126860639..126885878)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (129622918..129648157)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107987129 Neighboring gene zinc finger and BTB domain containing 43 Neighboring gene Ral GEF with PH domain and SH3 binding motif 1 Neighboring gene uncharacterized LOC105376279 Neighboring gene Sharpr-MPRA regulatory region 532 Neighboring gene angiopoietin like 2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ22470, KIAA1993, MGC24652

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in chromatin ISA
Inferred from Sequence Alignment
more info
 
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
zinc finger and BTB domain-containing protein 34

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001099270.4NP_001092740.2  zinc finger and BTB domain-containing protein 34 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL160169, AL354944
    Consensus CDS
    CCDS48023.1
    Related
    ENSP00000317534.4, ENST00000319119.4
  2. NM_001395198.1NP_001382127.1  zinc finger and BTB domain-containing protein 34 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL160169, AL354944
    Conserved Domains (4) summary
    sd00017
    Location:388408
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd18220
    Location:21140
    BTB_POZ_ZBTB34; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 34 (ZBTB34)
    pfam00096
    Location:442463
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:400425
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p13 Primary Assembly

    Range
    126860639..126885878
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005251989.4XP_005252046.1  zinc finger and BTB domain-containing protein 34 isoform X1

    Conserved Domains (4) summary
    sd00017
    Location:388408
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd18220
    Location:21140
    BTB_POZ_ZBTB34; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 34 (ZBTB34)
    pfam00096
    Location:442463
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:400425
    zf-H2C2_2; Zinc-finger double domain
  2. XM_011518699.3XP_011517001.1  zinc finger and BTB domain-containing protein 34 isoform X2

    See identical proteins and their annotated locations for XP_011517001.1

    UniProtKB/Swiss-Prot
    Q8NCN2
    UniProtKB/TrEMBL
    A0A0C4DFQ2
    Conserved Domains (5) summary
    smart00355
    Location:376398
    ZnF_C2H2; zinc finger
    sd00017
    Location:378398
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd18220
    Location:11130
    BTB_POZ_ZBTB34; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 34 (ZBTB34)
    pfam00096
    Location:432453
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:390415
    zf-H2C2_2; Zinc-finger double domain

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_203482.1: Suppressed sequence

    Description
    NM_203482.1: This RefSeq was permanently suppressed because it is primarily UTR sequence.
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