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DEFB133 defensin beta 133 (pseudogene) [ Homo sapiens (human) ]

Gene ID: 403339, updated on 5-Mar-2024

Summary

Official Symbol
DEFB133provided by HGNC
Official Full Name
defensin beta 133 (pseudogene)provided by HGNC
Primary source
HGNC:HGNC:31331
See related
Ensembl:ENSG00000214643 AllianceGenome:HGNC:31331
Gene type
pseudo
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
DEFB134
Summary
Predicted to be involved in defense response to bacterium and innate immune response. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See DEFB133 in Genome Data Viewer
Location:
6p12.3
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (49946101..49949444, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (49788997..49792341, complement)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101927020 Neighboring gene uncharacterized LOC101927048 Neighboring gene cysteine rich secretory protein 1 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr6:49859209-49860408 Neighboring gene MPRA-validated peak5842 silencer Neighboring gene defensin beta 114 Neighboring gene defensin beta 113

Genomic regions, transcripts, and products

General gene information

Markers

Other Names

  • beta-defensin 133
  • beta-defensin 134
  • defensin, beta 133

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables CCR6 chemokine receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables chemoattractant activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in cell chemotaxis IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in defense response to bacterium IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in innate immune response IEA
Inferred from Electronic Annotation
more info
 
involved_in positive chemotaxis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_163261.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL356586
    Related
    ENST00000620560.2

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

    Range
    49946101..49949444 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060930.1 Alternate T2T-CHM13v2.0

    Range
    49788997..49792341 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001166478.1: Suppressed sequence

    Description
    NM_001166478.1: This RefSeq was removed because it is now thought that this gene is a pseudogene.