Format

Send to:

Choose Destination

PLPP6 phospholipid phosphatase 6 [ Homo sapiens (human) ]

Gene ID: 403313, updated on 1-Jun-2020

Summary

Official Symbol
PLPP6provided by HGNC
Official Full Name
phospholipid phosphatase 6provided by HGNC
Primary source
HGNC:HGNC:23682
See related
Ensembl:ENSG00000205808 MIM:611666
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PDP1; PSDP; PPAPDC2; bA6J24.6
Orthologs

Genomic context

See PLPP6 in Genome Data Viewer
Location:
9p24.1
Exon count:
1
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 9 NC_000009.12 (4662294..4665258)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (4662294..4665274)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene solute carrier family 1 member 1 Neighboring gene spermatogenesis associated 6 like Neighboring gene ribosomal protein S6 pseudogene 11 Neighboring gene CDC37L1 divergent transcript Neighboring gene cell division cycle 37 like 1

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ46512, FLJ55089, FLJ90191, MGC15483

Gene Ontology Provided by GOA

Function Evidence Code Pubs
hydrolase activity TAS
Traceable Author Statement
more info
 
lipid phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
lipid phosphatase activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
cholesterol biosynthetic process TAS
Traceable Author Statement
more info
 
phospholipid dephosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
phospholipid dephosphorylation IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
phospholipid phosphatase 6
Names
PPAP2 domain-containing protein 2
phosphatidic acid phosphatase type 2 domain containing 2
phosphatidic acid phosphatase type 2 domain-containing protein 2
polyisoprenoid diphosphate phosphatase type 1
presqualene diphosphate phosphatase
NP_982278.3

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_203453.5NP_982278.3  phospholipid phosphatase 6

    See identical proteins and their annotated locations for NP_982278.3

    Status: VALIDATED

    Source sequence(s)
    AK128369, BC036833, DA416947
    Consensus CDS
    CCDS34981.1
    UniProtKB/Swiss-Prot
    Q8IY26
    Related
    ENSP00000371307.2, ENST00000381883.5
    Conserved Domains (2) summary
    COG0671
    Location:208292
    PgpB; Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]
    cd03391
    Location:118276
    PAP2_containing_2_like; PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_2. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to eukaryota, lacks functional characterization and may act as a ...

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p13 Primary Assembly

    Range
    4662294..4665258
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center