ESRRA estrogen related receptor alpha [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: ESRRAprovided by VGNC
Official Full Name: estrogen related receptor alphaprovided by VGNC
Primary source: VGNC:VGNC:54270
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as: ESTRRA
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 18

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	18	NC_051822.1 (53800958..53808348, complement)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	18	NC_006600.4 (51363416..51368398, complement)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	18	NC_049239.1 (53264070..53269055, complement)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	18	NC_049278.1 (52893602..52898808, complement)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	18	NC_049759.1 (52480190..52485175, complement)

Chromosome 18 - NC_051822.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

AR, ER alpha, and ER beta are differently expressed in canine prostate tissue
Title: Immunolocalization of androgen receptors, estrogen alpha receptors, and estrogen beta receptors in experimentally induced canine prostatic hyperplasia.
No statistical difference in staining of early follicle stages was noted; therefore, the oestrogen receptor is unlikely to be the controlling factor for the transition from telogen to anagen in the dog.
Title: Influence of inflammation and coat type on oestrogen receptor immunohistochemistry.

Submit: New GeneRIF Correction

General gene information

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Markers

BARC0081 (e-PCR)
- UniSTS:277893

Esrra (e-PCR), detects polymorphism
- UniSTS:496007

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables nuclear steroid receptor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info	PubMed
enables steroid binding	IEA Inferred from Electronic Annotation more info	PubMed
enables zinc ion binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: steroid hormone receptor ERR1

Names: ERR-alpha; nuclear receptor subfamily 3 group B member 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001002936.1 → NP_001002936.1 steroid hormone receptor ERR1

See identical proteins and their annotated locations for NP_001002936.1

Status: PROVISIONAL

Source sequence(s)

AY533243

UniProtKB/Swiss-Prot

Q6QMY5

Conserved Domains (2) summary

cd06946
Location:196 → 419

NR_LBD_ERR; The ligand binding domain of estrogen receptor-related nuclear receptors

cd07170
Location:73 → 168

NR_DBD_ERR; DNA-binding domain of estrogen related receptors (ERR) is composed of two C4-type zinc fingers

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051822.1 Reference ROS_Cfam_1.0

Range

53800958..53808348 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038423356.1 → XP_038279284.1 steroid hormone receptor ERR1 isoform X1

UniProtKB/TrEMBL

A0A8C0KN43, A0A8C0N011

Conserved Domains (2) summary

cd06946
Location:196 → 419

NR_LBD_ERR; The ligand binding domain of estrogen receptor-related nuclear receptors

cd07170
Location:73 → 168

NR_DBD_ERR; DNA-binding domain of estrogen related receptors (ERR) is composed of two C4-type zinc fingers
XM_038423357.1 → XP_038279285.1 steroid hormone receptor ERR1 isoform X1

UniProtKB/TrEMBL

A0A8C0KN43, A0A8C0N011

Conserved Domains (2) summary

cd06946
Location:196 → 419

NR_LBD_ERR; The ligand binding domain of estrogen receptor-related nuclear receptors

cd07170
Location:73 → 168

NR_DBD_ERR; DNA-binding domain of estrogen related receptors (ERR) is composed of two C4-type zinc fingers
XM_038423358.1 → XP_038279286.1 steroid hormone receptor ERR1 isoform X2

Conserved Domains (2) summary

cd06946
Location:53 → 276

NR_LBD_ERR; The ligand binding domain of estrogen receptor-related nuclear receptors

cl02596
Location:1 → 25

NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers