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tlr3 toll-like receptor 3 [ Danio rerio (zebrafish) ]

Gene ID: 403126, updated on 17-Nov-2020

Summary

Official Symbol
tlr3provided by ZNC
Official Full Name
toll-like receptor 3provided by ZNC
Primary source
ZFIN:ZDB-GENE-040219-7
See related
Ensembl:ENSDARG00000016065
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:123006
Orthologs

Genomic context

See tlr3 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
5
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (17892944..17898227)
105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (17200007..17205290)
103 previous assembly Zv9 (GCF_000002035.4) 1 NC_007112.5 (16634839..16640122)

Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene PDZ and LIM domain 3a Neighboring gene sorbin and SH3 domain containing 2a Neighboring gene cytochrome P450, family 4, subfamily V, polypeptide 8 Neighboring gene uncharacterized LOC101885541

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

General gene information

Homology

Clone Names

  • MGC123006

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
double-stranded RNA binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
signaling receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transmembrane signaling receptor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
MyD88-independent toll-like receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
defense response to virus IEA
Inferred from Electronic Annotation
more info
 
immune response IEA
Inferred from Electronic Annotation
more info
 
immune system process IEA
Inferred from Electronic Annotation
more info
 
inflammatory response IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
inflammatory response IEA
Inferred from Electronic Annotation
more info
 
innate immune response IEA
Inferred from Electronic Annotation
more info
 
positive regulation of chemokine production IEA
Inferred from Electronic Annotation
more info
 
positive regulation of cytokine production IEA
Inferred from Electronic Annotation
more info
 
positive regulation of inflammatory response IEA
Inferred from Electronic Annotation
more info
 
response to bacterium IDA
Inferred from Direct Assay
more info
PubMed 
response to exogenous dsRNA IEA
Inferred from Electronic Annotation
more info
 
response to virus IDA
Inferred from Direct Assay
more info
PubMed 
signal transduction IEA
Inferred from Electronic Annotation
more info
 
toll-like receptor 3 signaling pathway IEA
Inferred from Electronic Annotation
more info
 
toll-like receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
toll-like receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
membrane IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001013269.3NP_001013287.2  toll-like receptor 3 precursor

    See identical proteins and their annotated locations for NP_001013287.2

    Status: PROVISIONAL

    Source sequence(s)
    BC107955
    UniProtKB/TrEMBL
    Q32PW5
    Related
    ENSDARP00000014779.8, ENSDART00000013021.9
    Conserved Domains (5) summary
    smart00082
    Location:645683
    LRRCT; Leucine rich repeat C-terminal domain
    smart00255
    Location:756898
    TIR; Toll - interleukin 1 - resistance
    cd00116
    Location:49183
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:355378
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:562622
    LRR_8; Leucine rich repeat

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007112.7 Reference GRCz11 Primary Assembly

    Range
    17892944..17898227
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394471.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    238623..243906
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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