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pard3ab par-3 family cell polarity regulator alpha, b [ Danio rerio (zebrafish) ]

Gene ID: 403050, updated on 17-Nov-2020

Summary

Official Symbol
pard3abprovided by ZNC
Official Full Name
par-3 family cell polarity regulator alpha, bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030925-47
See related
Ensembl:ENSDARG00000010583
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
p; pa; baz; asip; par3; par-3; pard3; bazooka
Annotation information
Annotation category: partial on reference assembly
Orthologs

Genomic context

See pard3ab in Genome Data Viewer
Location:
chromosome: 2
Exon count:
22
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (43205021..43329698)
105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (43355603..43480280)
103 previous assembly Zv9 (GCF_000002035.4) 2 NC_007113.5 (43306139..43430816)

Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene finTRIM family, member 15 Neighboring gene cAMP responsive element modulator a Neighboring gene neuropilin 1b Neighboring gene neuropilin-1a-like

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
phosphatidylinositol binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
actin cytoskeleton organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
blood vessel lumenization IMP
Inferred from Mutant Phenotype
more info
PubMed 
camera-type eye development IMP
Inferred from Mutant Phenotype
more info
PubMed 
cell adhesion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cell cycle IEA
Inferred from Electronic Annotation
more info
 
cell division IEA
Inferred from Electronic Annotation
more info
 
cell migration in hindbrain IMP
Inferred from Mutant Phenotype
more info
PubMed 
central nervous system myelination IMP
Inferred from Mutant Phenotype
more info
PubMed 
contact inhibition IMP
Inferred from Mutant Phenotype
more info
PubMed 
dorsal aorta development IMP
Inferred from Mutant Phenotype
more info
PubMed 
embryonic eye morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
establishment of cell polarity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
establishment of centrosome localization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
establishment of centrosome localization IMP
Inferred from Mutant Phenotype
more info
PubMed 
establishment or maintenance of epithelial cell apical/basal polarity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
establishment or maintenance of epithelial cell apical/basal polarity IMP
Inferred from Mutant Phenotype
more info
PubMed 
microtubule cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
myelination in peripheral nervous system IMP
Inferred from Mutant Phenotype
more info
PubMed 
NOT myelination in peripheral nervous system IMP
Inferred from Mutant Phenotype
more info
PubMed 
NOT neural crest cell delamination IMP
Inferred from Mutant Phenotype
more info
PubMed 
NOT neural crest cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
neural crest cell migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
NOT neural crest cell migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
neuroblast proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
photoreceptor cell outer segment organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
protein localization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein localization to cell junction IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of cell shape IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of collateral sprouting in absence of injury IGI
Inferred from Genetic Interaction
more info
PubMed 
regulation of collateral sprouting in absence of injury IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
adherens junction IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
apical junction complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
apical plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
apical plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
cell cortex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cell-cell junction IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
endomembrane system IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
par-3 family cell polarity regulator alpha, b
Names
par-3 partitioning defective 3 homolog

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_205735.1NP_991298.1  par-3 family cell polarity regulator alpha, b

    See identical proteins and their annotated locations for NP_991298.1

    Status: PROVISIONAL

    Source sequence(s)
    AF465629
    UniProtKB/TrEMBL
    Q7T1R3
    Related
    ENSDARP00000056401.6, ENSDART00000056402.7
    Conserved Domains (3) summary
    smart00228
    Location:462547
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:589680
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam12053
    Location:1147
    DUF3534; Domain of unknown function (DUF3534)

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007113.7 Reference GRCz11 Primary Assembly

    Range
    43205021..43329698
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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