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polr1f RNA polymerase I subunit F [ Danio rerio (zebrafish) ]

Gene ID: 402856, updated on 11-Apr-2024

Summary

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Official Symbol
polr1fprovided by ZNC
Official Full Name
RNA polymerase I subunit Fprovided by ZNC
Primary source
ZFIN:ZDB-GENE-041007-3
See related
Ensembl:ENSDARG00000024416 AllianceGenome:ZFIN:ZDB-GENE-041007-3
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
twistnb
Summary
Predicted to enable DNA-directed 5'-3' RNA polymerase activity. Predicted to act upstream of or within transcription, DNA-templated. Predicted to be located in nucleolus. Predicted to be part of RNA polymerase I complex. Orthologous to human POLR1F (RNA polymerase I subunit F). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 19
Exon count:
5
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (2395117..2404147, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (2215326..2222243, complement)

Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene integrin, beta 8 Neighboring gene sp8 transcription factor a Neighboring gene transmembrane protein 196 Neighboring gene uncharacterized LOC103909188

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Essential genes for astroglial development and axon pathfinding during zebrafish embryogenesis. Barresi MJ, et al. Dev Dyn, 2010 Oct. PMID 20806318, Free PMC Article
  2. Identification of 315 genes essential for early zebrafish development. Amsterdam A, et al. Proc Natl Acad Sci U S A, 2004 Aug 31. PMID 15256591, Free PMC Article
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
acts_upstream_of_or_within DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within DNA-templated transcription initiation IEA
Inferred from Electronic Annotation
more info
  
involved_in DNA-templated transcription initiation IEA
Inferred from Electronic Annotation
more info
  
involved_in transcription elongation by RNA polymerase I IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of DNA-directed RNA polymerase complex IEA
Inferred from Electronic Annotation
more info
  
part_of RNA polymerase I complex IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
DNA-directed RNA polymerase I subunit RPA43
Names
DNA-directed RNA polymerase I subunit F
twist neighbor protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001007153.1 → NP_001007154.1  DNA-directed RNA polymerase I subunit RPA43

    See identical proteins and their annotated locations for NP_001007154.1

    Status: PROVISIONAL

    Source sequence(s)
    AY648783
    UniProtKB/Swiss-Prot
    Q6DRH6, Q6PHG8
    Related
    ENSDARP00000104602.1, ENSDART00000127578.4
    Conserved Domains (1) summary
    cd04328
    Location:48 → 134
    RNAP_I_Rpa43_N; RNAP_I_Rpa43_N: Rpa43, N-terminal ribonucleoprotein (RNP) domain. Rpa43 is a subunit of eukaryotic RNA polymerase (RNAP) I that is homologous to Rpb7 of eukaryotic RNAP II, Rpc25 of eukaryotic RNP III, and RpoE of archaeal RNAP. Rpa43 has two domains, an ...

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007130.7 Reference GRCz11 Primary Assembly

    Range
    2395117..2404147 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017352209.2 → XP_017207698.1  DNA-directed RNA polymerase I subunit RPA43 isoform X1

    UniProtKB/Swiss-Prot
    Q6DRH6, Q6PHG8
    UniProtKB/TrEMBL
    A0A8M6Z2B1
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6PHG8.2 GenPept UniProtKB/Swiss-Prot:Q6PHG8

Gene LinkOut

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