U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

GRIFIN galectin-related inter-fiber protein [ Homo sapiens (human) ]

Gene ID: 402635, updated on 8-Dec-2022

Summary

Official Symbol
GRIFINprovided by HGNC
Official Full Name
galectin-related inter-fiber proteinprovided by HGNC
Primary source
HGNC:HGNC:4577
See related
Ensembl:ENSG00000275572 MIM:619187; AllianceGenome:HGNC:4577
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to enable carbohydrate binding activity. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See GRIFIN in Genome Data Viewer
Location:
7p22.3
Exon count:
5
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (2474728..2476398, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (2588113..2589784, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (2514363..2516032, complement)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene CRISPRi-validated cis-regulatory element chr7.493 Neighboring gene carbohydrate sulfotransferase 12 Neighboring gene uncharacterized LOC107986759 Neighboring gene nonconserved acetylation island sequence 106 enhancer Neighboring gene LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase Neighboring gene microRNA 4648

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables carbohydrate binding IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
grifin
Names
putative grifin

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001394787.1NP_001381716.1  grifin

    Status: VALIDATED

    Source sequence(s)
    AC004840, KF459637
    Consensus CDS
    CCDS94046.1
    UniProtKB/Swiss-Prot
    A0A087WXP5
    Related
    ENSP00000481185.1, ENST00000614228.2
    Conserved Domains (1) summary
    smart00908
    Location:11131
    Gal-bind_lectin; Galactoside-binding lectin

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

    Range
    2474728..2476398 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060931.1 Alternate T2T-CHM13v2.0

    Range
    2588113..2589784 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NG_032051.2: Suppressed sequence

    Description
    NG_032051.2: This RefSeq was permanently suppressed because it is now thought that this gene is a transcribed pseudogene.
  2. NM_001291784.1: Suppressed sequence

    Description
    NM_001291784.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.