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FIGNL2 fidgetin like 2 [ Homo sapiens (human) ]

Gene ID: 401720, updated on 22-Aug-2021

Summary

Official Symbol
FIGNL2provided by HGNC
Official Full Name
fidgetin like 2provided by HGNC
Primary source
HGNC:HGNC:13287
See related
Ensembl:ENSG00000261308
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Broad expression in kidney (RPKM 1.7), testis (RPKM 0.4) and 15 other tissues See more
Orthologs
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Genomic context

See FIGNL2 in Genome Data Viewer
Location:
12q13.13
Exon count:
5
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 12 NC_000012.12 (51817892..51848718, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (52211683..52242502, complement)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene sodium voltage-gated channel alpha subunit 8 Neighboring gene heterogeneous nuclear ribonucleoprotein A3 pseudogene 10 Neighboring gene transmembrane and death domain 1 Neighboring gene FIGNL2 divergent transcript Neighboring gene filamin-B-like Neighboring gene ankyrin repeat domain 33

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables microtubule-severing ATPase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in microtubule severing IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
fidgetin-like protein 2
Names
putative fidgetin-like protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001013690.5NP_001013712.4  fidgetin-like protein 2

    See identical proteins and their annotated locations for NP_001013712.4

    Status: VALIDATED

    Source sequence(s)
    AC068987
    Consensus CDS
    CCDS86302.1
    UniProtKB/Swiss-Prot
    A6NMB9
    UniProtKB/TrEMBL
    Q6ZP58
    Conserved Domains (2) summary
    pfam09336
    Location:614650
    Vps4_C; Vps4 C terminal oligomerization domain
    cd19523
    Location:393555
    RecA-like_fidgetin; ATPase domain of fidgetin
  2. NM_001384995.1NP_001371924.1  fidgetin-like protein 2

    Status: VALIDATED

    Source sequence(s)
    AC068987
    Related
    ENSP00000491257.1, ENST00000618634.3
    Conserved Domains (2) summary
    pfam09336
    Location:614650
    Vps4_C; Vps4 C terminal oligomerization domain
    cd19523
    Location:393555
    RecA-like_fidgetin; ATPase domain of fidgetin
  3. NM_001384996.1NP_001371925.1  fidgetin-like protein 2

    Status: VALIDATED

    Source sequence(s)
    AC068987
    Conserved Domains (2) summary
    pfam09336
    Location:614650
    Vps4_C; Vps4 C terminal oligomerization domain
    cd19523
    Location:393555
    RecA-like_fidgetin; ATPase domain of fidgetin

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p13 Primary Assembly

    Range
    51817892..51848718 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017019299.1XP_016874788.1  fidgetin-like protein 2 isoform X2

  2. XM_017019298.1XP_016874787.1  fidgetin-like protein 2 isoform X1

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