GOLGA7B golgin A7 family member B [Homo sapiens (human)] - Gene

Summary

Official Symbol: GOLGA7Bprovided by HGNC
Official Full Name: golgin A7 family member Bprovided by HGNC
Primary source: HGNC:HGNC:31668
See related: Ensembl:ENSG00000155265 MIM:614189; AllianceGenome:HGNC:31668
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: C10orf132; C10orf133; bA459F3.4; bA451M19.3
Summary: Enables enzyme binding activity. Predicted to be involved in protein targeting to membrane. Predicted to be located in Golgi membrane and plasma membrane. Predicted to be part of palmitoyltransferase complex. [provided by Alliance of Genome Resources, Jul 2025]
Expression: Biased expression in brain (RPKM 7.2), skin (RPKM 7.1) and 11 other tissues See more
Orthologs: all
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Genomic context

Location:: 10q24.2

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2025_08	current	GRCh38.p14 (GCF_000001405.40)	10	NC_000010.11 (97849843..97871578)
RS_2025_08	current	T2T-CHM13v2.0 (GCF_009914755.1)	10	NC_060934.1 (98729980..98751715)
RS_2024_09	previous assembly	GRCh37.p13 (GCF_000001405.25)	10	NC_000010.10 (99609600..99631335)

Chromosome 10 - NC_000010.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Tissue-specific circular RNA induction during human fetal development
Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
BioProject: PRJNA270632
Publication: PMID 26076956
Analysis date: Mon Apr 2 22:54:59 2018

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Golgin A7 family member B (GOLGA7B) is a plausible novel gene associating high glycaemic index diet with acne vulgaris.
Title: Golgin A7 family member B (GOLGA7B) is a plausible novel gene associating high glycaemic index diet with acne vulgaris.
This work uncovers a novel mechanism of DHHC5 regulation by Golga7b and demonstrates a role for the DHHC5/Golga7b complex in the regulation of cell adhesion.
Title: S-acylated Golga7b stabilises DHHC5 at the plasma membrane to regulate cell adhesion.

Submit: New GeneRIF Correction

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
Gene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP Consortia. EBI GWAS Catalog EBI GWAS CatalogPubMed

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

D10S1353E (e-PCR)
- UniSTS:151364

D10S1393E (e-PCR)
- UniSTS:151390

SHGC-78664 (e-PCR)
- UniSTS:102113

D10S2197 (e-PCR)
- UniSTS:42728

Gene Ontology Provided by GOA

Function	Evidence Code	Pubs
enables enzyme binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in protein targeting to membrane	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in Golgi membrane	IEA Inferred from Electronic Annotation more info
part_of palmitoyltransferase complex	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	EXP Inferred from Experiment more info	PubMed
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: golgin subfamily A member 7B

Names: golgi autoantigen, golgin subfamily a, 7B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.