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GOLGA7B golgin A7 family member B [ Homo sapiens (human) ]

Gene ID: 401647, updated on 28-Aug-2022

Summary

Official Symbol
GOLGA7Bprovided by HGNC
Official Full Name
golgin A7 family member Bprovided by HGNC
Primary source
HGNC:HGNC:31668
See related
Ensembl:ENSG00000155265 MIM:614189; AllianceGenome:HGNC:31668
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C10orf132; C10orf133; bA459F3.4; bA451M19.3
Summary
Enables enzyme binding activity. Predicted to be involved in peptidyl-L-cysteine S-palmitoylation and protein targeting to membrane. Predicted to be located in Golgi membrane. Predicted to be part of palmitoyltransferase complex. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in brain (RPKM 7.2), skin (RPKM 7.1) and 11 other tissues See more
Orthologs
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Genomic context

See GOLGA7B in Genome Data Viewer
Location:
10q24.2
Exon count:
5
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (97849843..97871578)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (98729980..98751715)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (99609600..99631335)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 10024 Neighboring gene uncharacterized LOC107984260 Neighboring gene GOLGA7B divergent transcript Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr10:99641761-99642960 Neighboring gene cartilage acidic protein 1 Neighboring gene microRNA 3085

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Phenotypes

EBI GWAS Catalog

Description
Gene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP Consortia.
EBI GWAS Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ43465, MGC131701

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables enzyme binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in peptidyl-L-cysteine S-palmitoylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in protein targeting to membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
 
part_of palmitoyltransferase complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
golgin subfamily A member 7B
Names
golgi autoantigen, golgin subfamily a, 7B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001010917.3NP_001010917.1  golgin subfamily A member 7B

    See identical proteins and their annotated locations for NP_001010917.1

    Status: VALIDATED

    Source sequence(s)
    AK125454, AL358938, AW172573, BC008047, BC110810, BI754792, BM713854, BQ950672, CA308047, DN831741
    Consensus CDS
    CCDS31265.1
    UniProtKB/Swiss-Prot
    Q2TAP0, Q5T4F5
    UniProtKB/TrEMBL
    Q6ZUQ1
    Related
    ENSP00000359634.1, ENST00000370602.6
    Conserved Domains (1) summary
    pfam10256
    Location:21133
    Erf4; Golgin subfamily A member 7/ERF4 family

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

    Range
    97849843..97871578
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060934.1 Alternate T2T-CHM13v2.0

    Range
    98729980..98751715
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)