U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

SNX30 sorting nexin family member 30 [ Homo sapiens (human) ]

Gene ID: 401548, updated on 23-Nov-2023

Summary

Official Symbol
SNX30provided by HGNC
Official Full Name
sorting nexin family member 30provided by HGNC
Primary source
HGNC:HGNC:23685
See related
Ensembl:ENSG00000148158 AllianceGenome:HGNC:23685
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ATG24A
Summary
Predicted to enable phosphatidylinositol binding activity. Predicted to be involved in protein transport. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in kidney (RPKM 13.0), lung (RPKM 12.9) and 24 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See SNX30 in Genome Data Viewer
Location:
9q32
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (112749723..112885769)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 9 NC_060933.1 (124920960..125057645)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (115513040..115637267)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene HSDL2 antisense RNA 1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20192 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20193 Neighboring gene KIAA1958 Neighboring gene Sharpr-MPRA regulatory region 4745 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:115309395-115309946 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr9:115309947-115310499 Neighboring gene H3K27ac hESC enhancer GRCh37_chr9:115310500-115311051 Neighboring gene Sharpr-MPRA regulatory region 8480 Neighboring gene NANOG hESC enhancer GRCh37_chr9:115313867-115314374 Neighboring gene ReSE screen-validated silencer GRCh37_chr9:115357836-115358025 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:115380828-115381410 Neighboring gene MPRA-validated peak7319 silencer Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28826 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20194 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28827 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28828 Neighboring gene INTS3 and NABP interacting protein Neighboring gene H3K27ac hESC enhancer GRCh37_chr9:115512887-115513808 Neighboring gene H3K27ac hESC enhancer GRCh37_chr9:115513809-115514728 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr9:115516859-115517473 Neighboring gene H3K27ac hESC enhancer GRCh37_chr9:115517474-115518087 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:115518123-115518802 Neighboring gene SNX30 divergent transcript Neighboring gene Sharpr-MPRA regulatory region 12854 Neighboring gene OCT4-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:115565661-115566288 Neighboring gene OCT4-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:115566289-115566914 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:115572830-115573740 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20196 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28830 Neighboring gene MPRA-validated peak7321 silencer Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20197 Neighboring gene NANOG hESC enhancer GRCh37_chr9:115608506-115609059 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:115609080-115609580 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:115610366-115610938 Neighboring gene H3K27ac hESC enhancer GRCh37_chr9:115628995-115629496 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28831 Neighboring gene solute carrier family 46 member 2 Neighboring gene major urinary protein, pseudogene Neighboring gene zinc finger protein 883

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • FLJ26481, FLJ34280, FLJ35589, FLJ44686, FLJ45069, FLJ46877

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables phosphatidylinositol binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in autophagy of mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in endocytic recycling IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in piecemeal microautophagy of the nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in positive regulation of autophagosome assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in protein transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in protein transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in reticulophagy IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in early endosome IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in early endosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in early endosome membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in phagophore assembly site IBA
Inferred from Biological aspect of Ancestor
more info
 

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001012994.2NP_001013012.1  sorting nexin-30

    See identical proteins and their annotated locations for NP_001013012.1

    Status: VALIDATED

    Source sequence(s)
    AA401207, AK127013, AL139041, AL360235, AL390067, BG699098, BX367137
    Consensus CDS
    CCDS43865.1
    UniProtKB/Swiss-Prot
    Q5VWJ9
    Related
    ENSP00000363349.3, ENST00000374232.8
    Conserved Domains (2) summary
    cd06860
    Location:91206
    PX_SNX7_30_like; The phosphoinositide binding Phox Homology domain of Sorting Nexins 7 and 30
    cd07667
    Location:190429
    BAR_SNX30; The Bin/Amphiphysin/Rvs (BAR) domain of Sorting Nexin 30

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

    Range
    112749723..112885769
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047423393.1XP_047279349.1  sorting nexin-30 isoform X1

  2. XM_047423395.1XP_047279351.1  sorting nexin-30 isoform X2

RNA

  1. XR_007061307.1 RNA Sequence

  2. XR_007061301.1 RNA Sequence

  3. XR_007061302.1 RNA Sequence

  4. XR_007061303.1 RNA Sequence

  5. XR_007061304.1 RNA Sequence

  6. XR_007061305.1 RNA Sequence

  7. XR_007061306.1 RNA Sequence

  8. XR_007061308.1 RNA Sequence

  9. XR_007061309.1 RNA Sequence

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060933.1 Alternate T2T-CHM13v2.0

    Range
    124920960..125057645
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054362972.1XP_054218947.1  sorting nexin-30 isoform X1

  2. XM_054362973.1XP_054218948.1  sorting nexin-30 isoform X2

RNA

  1. XR_008488030.1 RNA Sequence

  2. XR_008488024.1 RNA Sequence

  3. XR_008488025.1 RNA Sequence

  4. XR_008488026.1 RNA Sequence

  5. XR_008488027.1 RNA Sequence

  6. XR_008488028.1 RNA Sequence

  7. XR_008488029.1 RNA Sequence

  8. XR_008488031.1 RNA Sequence

  9. XR_008488032.1 RNA Sequence