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SNX30 sorting nexin family member 30 [ Homo sapiens (human) ]

Gene ID: 401548, updated on 6-Nov-2022

Summary

Official Symbol
SNX30provided by HGNC
Official Full Name
sorting nexin family member 30provided by HGNC
Primary source
HGNC:HGNC:23685
See related
Ensembl:ENSG00000148158 AllianceGenome:HGNC:23685
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ATG24A
Summary
Predicted to enable phosphatidylinositol binding activity. Predicted to be involved in protein transport. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in kidney (RPKM 13.0), lung (RPKM 12.9) and 24 other tissues See more
Orthologs
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Genomic context

See SNX30 in Genome Data Viewer
Location:
9q32
Exon count:
14
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (112749723..112885769)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 9 NC_060933.1 (124921996..125046429)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (115513040..115637267)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene KIAA1958 Neighboring gene Sharpr-MPRA regulatory region 8480 Neighboring gene INTS3 and NABP interacting protein Neighboring gene Sharpr-MPRA regulatory region 12854 Neighboring gene solute carrier family 46 member 2 Neighboring gene major urinary protein, pseudogene Neighboring gene zinc finger protein 883

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ26481, FLJ34280, FLJ35589, FLJ44686, FLJ45069, FLJ46877

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables phosphatidylinositol binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in autophagy of mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in endocytic recycling IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in piecemeal microautophagy of the nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in positive regulation of autophagosome assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in protein transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in protein transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in reticulophagy IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in early endosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in early endosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in early endosome membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in phagophore assembly site IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001012994.2NP_001013012.1  sorting nexin-30

    See identical proteins and their annotated locations for NP_001013012.1

    Status: VALIDATED

    Source sequence(s)
    AA401207, AK127013, AL139041, AL360235, AL390067, BG699098, BX367137
    Consensus CDS
    CCDS43865.1
    UniProtKB/Swiss-Prot
    Q5VWJ9
    Related
    ENSP00000363349.3, ENST00000374232.8
    Conserved Domains (2) summary
    cd06860
    Location:91206
    PX_SNX7_30_like; The phosphoinositide binding Phox Homology domain of Sorting Nexins 7 and 30
    cd07667
    Location:190429
    BAR_SNX30; The Bin/Amphiphysin/Rvs (BAR) domain of Sorting Nexin 30

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

    Range
    112749723..112885769
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047423393.1XP_047279349.1  sorting nexin-30 isoform X1

  2. XM_047423395.1XP_047279351.1  sorting nexin-30 isoform X2

RNA

  1. XR_007061307.1 RNA Sequence

  2. XR_007061301.1 RNA Sequence

  3. XR_007061302.1 RNA Sequence

  4. XR_007061303.1 RNA Sequence

  5. XR_007061304.1 RNA Sequence

  6. XR_007061305.1 RNA Sequence

  7. XR_007061306.1 RNA Sequence

  8. XR_007061308.1 RNA Sequence

  9. XR_007061309.1 RNA Sequence

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060933.1 Alternate T2T-CHM13v2.0

    Range
    124921996..125046429
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)