Format

Send to:

Choose Destination

Trpml Transient receptor potential cation channel, mucolipin [ Drosophila melanogaster (fruit fly) ]

Gene ID: 40152, updated on 8-Oct-2018

Summary

Official Symbol
Trpmlprovided by FlyBase
Official Full Name
Transient receptor potential cation channel, mucolipinprovided by FlyBase
Primary source
FLYBASE:FBgn0262516
Locus tag
Dmel_CG8743
Gene type
protein coding
RNA name
transient receptor potential cation channel, mucolipin
RefSeq status
REVIEWED
Organism
Drosophila melanogaster (old-lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG8743; CT25240; Dmel\CG8743; DmTRPML; l(3)76BDi; trpml; TRPML

Genomic context

See Trpml in Genome Data Viewer
Location:
76C2-76C2; 3-46 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.13 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (19714418..19718328, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (19707518..19711428, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene vermiform Neighboring gene serpentine Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
calcium channel activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
cation channel activity IDA
Inferred from Direct Assay
more info
PubMed 
cation channel activity ISS
Inferred from Sequence or Structural Similarity
more info
 
intracellular ligand-gated ion channel activity IDA
Inferred from Direct Assay
more info
PubMed 
phosphatidylinositol-3,5-bisphosphate binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
autophagosome maturation IMP
Inferred from Mutant Phenotype
more info
PubMed 
autophagy IMP
Inferred from Mutant Phenotype
more info
PubMed 
calcium ion transport ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
cation transport IDA
Inferred from Direct Assay
more info
PubMed 
cation transport ISS
Inferred from Sequence or Structural Similarity
more info
 
cellular calcium ion homeostasis IMP
Inferred from Mutant Phenotype
more info
PubMed 
lateral inhibition IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of growth of symbiont in host IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of TOR signaling IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of synaptic growth at neuromuscular junction IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
cation channel complex ISS
Inferred from Sequence or Structural Similarity
more info
 
endolysosome membrane IDA
Inferred from Direct Assay
more info
PubMed 
late endosome IDA
Inferred from Direct Assay
more info
PubMed 
late endosome membrane IDA
Inferred from Direct Assay
more info
PubMed 
lysosomal membrane IDA
Inferred from Direct Assay
more info
PubMed 
lysosome IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
transient receptor potential cation channel, mucolipin
Names
CG8743-PA
TRP mucolipin
Trpml-PA
l(3)76BDi
transient receptor potential cation channel, mucolipin ortholog
transient receptor potential mucolipin

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    19714418..19718328 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_140888.4NP_649145.1  transient receptor potential cation channel, mucolipin [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_649145.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VW35
    Related
    FBpp0074720, FBtr0074952
    Conserved Domains (1) summary
    pfam00520
    Location:403578
    Ion_trans; Ion transport protein
Support Center