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TMEM215 transmembrane protein 215 [ Homo sapiens (human) ]

Gene ID: 401498, updated on 22-Sep-2022

Summary

Official Symbol
TMEM215provided by HGNC
Official Full Name
transmembrane protein 215provided by HGNC
Primary source
HGNC:HGNC:33816
See related
Ensembl:ENSG00000188133 AllianceGenome:HGNC:33816
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in endometrium (RPKM 2.5), testis (RPKM 1.2) and 3 other tissues See more
Orthologs
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Genomic context

See TMEM215 in Genome Data Viewer
Location:
9p21.1
Exon count:
3
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (32783540..32789201)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 9 NC_060933.1 (32799741..32805402)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (32783538..32789199)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105376017 Neighboring gene uncharacterized LOC105376016 Neighboring gene ribosomal protein S11 pseudogene 4 Neighboring gene uncharacterized LOC107987060 Neighboring gene bolA family member 3 pseudogene 4

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Phenotypes

EBI GWAS Catalog

Description
A genome-wide association study of host genetic determinants of the antibody response to Anthrax Vaccine Adsorbed.
EBI GWAS Catalog

General gene information

Homology

Clone Names

  • FLJ43330, DKFZp686I2292

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in negative regulation of retinal cell programmed cell death IEA
Inferred from Electronic Annotation
more info
 
involved_in sprouting angiogenesis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_212558.3NP_997723.2  transmembrane protein 215

    See identical proteins and their annotated locations for NP_997723.2

    Status: VALIDATED

    Source sequence(s)
    AL157884, BM681172, BX647550
    Consensus CDS
    CCDS6530.1
    UniProtKB/Swiss-Prot
    Q68D42, Q6ZUU2
    Related
    ENSP00000345468.5, ENST00000342743.6
    Conserved Domains (1) summary
    pfam15746
    Location:1235
    TMEM215; TMEM215 family

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

    Range
    32783540..32789201
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_929252.2 RNA Sequence

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060933.1 Alternate T2T-CHM13v2.0

    Range
    32799741..32805402
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)