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RAB19 RAB19, member RAS oncogene family [ Homo sapiens (human) ]

Gene ID: 401409, updated on 23-Nov-2021

Summary

Official Symbol
RAB19provided by HGNC
Official Full Name
RAB19, member RAS oncogene familyprovided by HGNC
Primary source
HGNC:HGNC:19982
See related
Ensembl:ENSG00000146955
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
RAB19B
Expression
Broad expression in colon (RPKM 1.1), thyroid (RPKM 1.0) and 15 other tissues See more
Orthologs
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Genomic context

See RAB19 in Genome Data Viewer
Location:
7q34
Exon count:
5
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 7 NC_000007.14 (140403740..140427974)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (140103858..140127774)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene solute carrier family 37 member 3 Neighboring gene RNA, 5S ribosomal pseudogene 247 Neighboring gene RNA, 5S ribosomal pseudogene 248 Neighboring gene nucleoside diphosphate kinase, mitochondrial-like Neighboring gene makorin ring finger protein 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 
enables GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in autophagosome assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in intracellular protein transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in endomembrane system IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in extracellular exosome HDA PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
ras-related protein Rab-19
Names
GTP-binding protein RAB19B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001008749.3NP_001008749.2  ras-related protein Rab-19

    See identical proteins and their annotated locations for NP_001008749.2

    Status: VALIDATED

    Source sequence(s)
    AC069335, BC140796, DN996121, DY655778
    Consensus CDS
    CCDS34762.2
    UniProtKB/Swiss-Prot
    A4D1S5
    Related
    ENSP00000440167.1, ENST00000537763.6
    Conserved Domains (1) summary
    cd01864
    Location:15179
    Rab19; Rab GTPase family 19 (Rab19)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p13 Primary Assembly

    Range
    140403740..140427974
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005249998.3XP_005250055.1  ras-related protein Rab-19 isoform X3

    Conserved Domains (2) summary
    smart00175
    Location:18168
    RAB; Rab subfamily of small GTPases
    cl21455
    Location:15165
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  2. XM_005249997.3XP_005250054.1  ras-related protein Rab-19 isoform X2

    Conserved Domains (2) summary
    cd01864
    Location:15167
    Rab19; Rab GTPase family 19 (Rab19)
    smart00175
    Location:18170
    RAB; Rab subfamily of small GTPases
  3. XM_005249996.3XP_005250053.1  ras-related protein Rab-19 isoform X1

    See identical proteins and their annotated locations for XP_005250053.1

    UniProtKB/Swiss-Prot
    A4D1S5
    Conserved Domains (1) summary
    cd01864
    Location:15179
    Rab19; Rab GTPase family 19 (Rab19)
  4. XM_017012207.1XP_016867696.1  ras-related protein Rab-19 isoform X1

    UniProtKB/Swiss-Prot
    A4D1S5
    Related
    ENSP00000348778.3, ENST00000356407.3
    Conserved Domains (1) summary
    cd01864
    Location:15179
    Rab19; Rab GTPase family 19 (Rab19)
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