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FAM177B family with sequence similarity 177 member B [ Homo sapiens (human) ]

Gene ID: 400823, updated on 12-Oct-2019

Summary

Official Symbol
FAM177Bprovided by HGNC
Official Full Name
family with sequence similarity 177 member Bprovided by HGNC
Primary source
HGNC:HGNC:34395
See related
Ensembl:ENSG00000197520
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Biased expression in stomach (RPKM 8.5), colon (RPKM 2.2) and 6 other tissues See more
Orthologs

Genomic context

See FAM177B in Genome Data Viewer
Location:
1q41
Exon count:
9
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (222737216..222772193)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (222910558..222926932)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene prefoldin subunit 5 pseudogene Neighboring gene MIA SH3 domain ER export factor 3 Neighboring gene axin interactor, dorsalization associated Neighboring gene uncharacterized LOC105372984 Neighboring gene BRO1 domain and CAAX motif containing Neighboring gene dispatched RND transporter family member 1 Neighboring gene NADH:ubiquinone oxidoreductase subunit B1 pseudogene 2 Neighboring gene 1q41-q42 HERV-mediated distal recombination region

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Markers

Homology

Clone Names

  • FLJ43505

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001324080.1NP_001311009.1  protein FAM177B

    Status: VALIDATED

    Source sequence(s)
    AL392172
    Consensus CDS
    CCDS1535.2
    UniProtKB/Swiss-Prot
    A6PVY3
    Related
    ENSP00000414451.2, ENST00000445590.3
    Conserved Domains (1) summary
    pfam14774
    Location:8120
    FAM177; FAM177 family
  2. NM_207468.2NP_997351.2  protein FAM177B

    See identical proteins and their annotated locations for NP_997351.2

    Status: VALIDATED

    Source sequence(s)
    AL392172, CA848039
    Consensus CDS
    CCDS1535.2
    UniProtKB/Swiss-Prot
    A6PVY3
    Conserved Domains (1) summary
    pfam14774
    Location:8120
    FAM177; FAM177 family

RNA

  1. NR_136691.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AK125494
    Related
    ENST00000391880.6

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20190905

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    222737216..222772193
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017001280.1XP_016856769.1  protein FAM177B isoform X1

    UniProtKB/Swiss-Prot
    A6PVY3
    Related
    ENSP00000354070.2, ENST00000360827.6
    Conserved Domains (1) summary
    pfam14774
    Location:8120
    FAM177; FAM177 family
  2. XM_017001285.1XP_016856774.1  protein FAM177B isoform X4

  3. XM_017001283.1XP_016856772.1  protein FAM177B isoform X2

  4. XM_017001284.1XP_016856773.1  protein FAM177B isoform X3

  5. XM_017001281.1XP_016856770.1  protein FAM177B isoform X1

    UniProtKB/Swiss-Prot
    A6PVY3
    Conserved Domains (1) summary
    pfam14774
    Location:8120
    FAM177; FAM177 family
  6. XM_017001279.1XP_016856768.1  protein FAM177B isoform X1

    UniProtKB/Swiss-Prot
    A6PVY3
    Conserved Domains (1) summary
    pfam14774
    Location:8120
    FAM177; FAM177 family
  7. XM_017001282.1XP_016856771.1  protein FAM177B isoform X1

    UniProtKB/Swiss-Prot
    A6PVY3
    Conserved Domains (1) summary
    pfam14774
    Location:8120
    FAM177; FAM177 family
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