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LOC400499 putative uncharacterized protein LOC400499 [ Homo sapiens (human) ]

Gene ID: 400499, updated on 21-Mar-2023

Summary

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Gene symbol
LOC400499
Gene description
putative uncharacterized protein LOC400499
See related
Ensembl:ENSG00000188897
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Low expression observed in reference dataset See more
Orthologs
all
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Genomic context

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See LOC400499 in Genome Data Viewer
Location:
16p13.13
Exon count:
69
Annotation release Status Assembly Chr Location
RS_2023_03 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (11372015..11527577, complement)
RS_2023_03 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (11408320..11563682, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (11465872..11621103, complement)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105371082 Neighboring gene uncharacterized LOC105371083 Neighboring gene mitochondrial ribosomal protein L18 pseudogene Neighboring gene RecQ mediated genome instability 2 Neighboring gene uncharacterized LOC101927131 Neighboring gene uncharacterized LOC124903807 Neighboring gene Sharpr-MPRA regulatory region 8116 Neighboring gene lipopolysaccharide induced TNF factor Neighboring gene Sharpr-MPRA regulatory region 4417 Neighboring gene uncharacterized LOC124903643 Neighboring gene Sharpr-MPRA regulatory region 8349

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome. Yao Z, et al. Mol Cell, 2017 Jan 19. PMID 28065597, Free PMC Article

See citations in PubMed for homologs of this gene provided by HomoloGene

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

General protein information

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Preferred Names
putative uncharacterized protein LOC400499

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001370704.1 → NP_001357633.1  putative uncharacterized protein LOC400499 isoform 1 precursor

    Status: VALIDATED

    Source sequence(s)
    AC099489, KF573656
    Consensus CDS
    CCDS92108.1
    UniProtKB/TrEMBL
    A0A8Q3SIG1
    Related
    ENSP00000512464.1, ENST00000696174.1
    Conserved Domains (3) summary
    cl26969
    Location:50 → 585
    Vitellogenin_N; Lipoprotein amino terminal region
    pfam08742
    Location:3262 → 3308
    C8; C8 domain
    pfam09172
    Location:618 → 910
    DUF1943; Domain of unknown function (DUF1943)

  2. NM_001395505.1 → NP_001382434.1  putative uncharacterized protein LOC400499 isoform 2 precursor

    Status: VALIDATED

    Source sequence(s)
    AC099489, KF573656
    Consensus CDS
    CCDS92107.1
    UniProtKB/TrEMBL
    M0QZD8
    Related
    ENSP00000470478.3, ENST00000598234.6
    Conserved Domains (2) summary
    smart00832
    Location:3207 → 3253
    C8; This domain contains 8 conserved cysteine residues
    cl26969
    Location:50 → 585
    Vitellogenin_N; Lipoprotein amino terminal region

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_03

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

    Range
    11372015..11527577 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017023946.1 → XP_016879435.1  putative uncharacterized protein LOC400499 isoform X1

  2. XM_047434105.1 → XP_047290061.1  putative uncharacterized protein LOC400499 isoform X2

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060940.1 Alternate T2T-CHM13v2.0

    Range
    11408320..11563682 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054380319.1 → XP_054236294.1  putative uncharacterized protein LOC400499 isoform X1

  2. XM_054380320.1 → XP_054236295.1  putative uncharacterized protein LOC400499 isoform X2

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001013671.1: Suppressed sequence

    Description
    NM_001013671.1: This RefSeq record was removed by NCBI staff. Contact info@ncbi.nlm.nih.gov for further information.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6ZTK2.1 GenPept UniProtKB/Swiss-Prot:Q6ZTK2

Gene LinkOut

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