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C12orf76 chromosome 12 open reading frame 76 [ Homo sapiens (human) ]

Gene ID: 400073, updated on 4-Nov-2022

Summary

Official Symbol
C12orf76provided by HGNC
Official Full Name
chromosome 12 open reading frame 76provided by HGNC
Primary source
HGNC:HGNC:33790
See related
Ensembl:ENSG00000174456 AllianceGenome:HGNC:33790
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in brain (RPKM 19.9), testis (RPKM 3.8) and 20 other tissues See more
Orthologs
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Genomic context

See C12orf76 in Genome Data Viewer
Location:
12q24.11
Exon count:
7
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 12 NC_000012.12 (110041177..110073635, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 12 NC_060936.1 (110016870..110049334, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (110478982..110511440, complement)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene GIT ArfGAP 2 Neighboring gene uncharacterized LOC124903013 Neighboring gene ankyrin repeat domain 13A Neighboring gene Sharpr-MPRA regulatory region 2512 Neighboring gene CRISPRi-validated cis-regulatory element chr12.3588 Neighboring gene uncharacterized LOC105369976 Neighboring gene Sharpr-MPRA regulatory region 13461

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ11385, FLJ40142

General protein information

Preferred Names
uncharacterized protein C12orf76

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001389625.1NP_001376554.1  uncharacterized protein C12orf76 isoform 2 precursor

    Status: VALIDATED

    Source sequence(s)
    AC007546
    Consensus CDS
    CCDS91748.1
    UniProtKB/TrEMBL
    A0A087WX00
    Related
    ENSP00000480634.2, ENST00000615315.2

RNA

  1. NR_148514.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC007546
    Related
    ENST00000687036.1
  2. NR_148515.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC007546, BC046185
    Related
    ENST00000687999.1
  3. NR_148517.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC007546, AK021447, BC046185

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p14 Primary Assembly

    Range
    110041177..110073635 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060936.1 Alternate T2T-CHM13v2.0

    Range
    110016870..110049334 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_207435.3: Suppressed sequence

    Description
    NM_207435.3: This RefSeq was removed because currently there is support for the transcript but not for the protein.