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Eip75B Ecdysone-induced protein 75B [ Drosophila melanogaster (fruit fly) ]

Gene ID: 39999, updated on 10-Oct-2019

Summary

Official Symbol
Eip75Bprovided by FlyBase
Official Full Name
Ecdysone-induced protein 75Bprovided by FlyBase
Primary source
FLYBASE:FBgn0000568
Locus tag
Dmel_CG8127
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
57B; 75B; anon-WO0172774.31; anon-WO0172774.32; BcDNA:GM02640; CG8127; dE75; DmE75; DmE75A; DmE75B; Dmel\CG8127; E75; E75-C; E75A; E75B; E75C; Eip75; EiP75; Eip75 A; Eip75A; eip75B; EP1121b; l(3)07041; l(3)j11A6; l(3)j12E8; l(3)j3A6; l(3)j5E1; l(3)neo25; Mgn00274; NR1D3; Rev-Erb

Genomic context

See Eip75B in Genome Data Viewer
Location:
75A10-75B6; 3-45 cM
Exon count:
13
Annotation release Status Assembly Chr Location
Release 6.26 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (17950953..18064696, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (17944053..18057796, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR43174 Neighboring gene long non-coding RNA:CR45393 Neighboring gene long non-coding RNA:CR45921 Neighboring gene ncRNA Neighboring gene long non-coding RNA:CR45922 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
RNA polymerase II regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
heme binding IDA
Inferred from Direct Assay
more info
PubMed 
nuclear receptor activity IEA
Inferred from Electronic Annotation
more info
 
nuclear receptor activity NAS
Non-traceable Author Statement
more info
PubMed 
nuclear receptor transcription coactivator activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
signaling receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
steroid hormone receptor activity IEA
Inferred from Electronic Annotation
more info
 
transcription factor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transcription regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ecdysis, chitin-based cuticle IMP
Inferred from Mutant Phenotype
more info
PubMed 
hormone-mediated signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
molting cycle, chitin-based cuticle IMP
Inferred from Mutant Phenotype
more info
PubMed 
multicellular organism development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of transcription by RNA polymerase II ISS
Inferred from Sequence or Structural Similarity
more info
 
oogenesis NAS
Non-traceable Author Statement
more info
PubMed 
positive regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of ecdysteroid metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of gene expression IDA
Inferred from Direct Assay
more info
PubMed 
response to ecdysone IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to lipid IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
RNA polymerase II transcription factor complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
Ecdysone-induced protein 75B
Names
CG8127-PA
CG8127-PB
CG8127-PC
CG8127-PD
CG8127-PE
CG8127-PF
CG8127-PG
E75 nuclear receptor
Eip75B-PA
Eip75B-PB
Eip75B-PC
Eip75B-PD
Eip75B-PE
Eip75B-PF
Eip75B-PG
ecdysone induced protein 75
ecdysone inducible protein 75B
ecdysone-induced protein 75

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    17950953..18064696 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001259893.2NP_001246822.1  Ecdysone-induced protein 75B, isoform F [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001246822.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P13055
    UniProtKB/TrEMBL
    M9NED3
    Related
    FBpp0297726, FBtr0306814
    Conserved Domains (2) summary
    cd06940
    Location:609796
    NR_LBD_REV_ERB; The ligand binding domain of REV-ERB receptors, members of the nuclear receptor superfamily
    cd07166
    Location:453541
    NR_DBD_REV_ERB; DNA-binding domain of REV-ERB receptor-like is composed of two C4-type zinc fingers
  2. NM_168756.2NP_730322.1  Ecdysone-induced protein 75B, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_730322.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P17671
    Related
    FBpp0074915, FBtr0075149
    Conserved Domains (2) summary
    cd06940
    Location:396583
    NR_LBD_REV_ERB; The ligand binding domain of REV-ERB receptors, members of the nuclear receptor superfamily
    cd07166
    Location:240328
    NR_DBD_REV_ERB; DNA-binding domain of REV-ERB receptor-like is composed of two C4-type zinc fingers
  3. NM_079409.3NP_524133.2  Ecdysone-induced protein 75B, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_524133.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P17672
    Related
    FBpp0074916, FBtr0075150
    Conserved Domains (2) summary
    cd06940
    Location:552739
    NR_LBD_REV_ERB; The ligand binding domain of REV-ERB receptors, members of the nuclear receptor superfamily
    cl02596
    Location:415484
    NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers
  4. NM_001259892.1NP_001246821.1  Ecdysone-induced protein 75B, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001246821.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P13055
    UniProtKB/TrEMBL
    M9NED3
    Related
    FBpp0297725, FBtr0306813
    Conserved Domains (2) summary
    cd06940
    Location:609796
    NR_LBD_REV_ERB; The ligand binding domain of REV-ERB receptors, members of the nuclear receptor superfamily
    cd07166
    Location:453541
    NR_DBD_REV_ERB; DNA-binding domain of REV-ERB receptor-like is composed of two C4-type zinc fingers
  5. NM_168755.1NP_730321.1  Ecdysone-induced protein 75B, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_730321.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P13055
    UniProtKB/TrEMBL
    M9NED3
    Related
    FBpp0074914, FBtr0075148
    Conserved Domains (2) summary
    cd06940
    Location:609796
    NR_LBD_REV_ERB; The ligand binding domain of REV-ERB receptors, members of the nuclear receptor superfamily
    cd07166
    Location:453541
    NR_DBD_REV_ERB; DNA-binding domain of REV-ERB receptor-like is composed of two C4-type zinc fingers
  6. NM_001316451.1NP_001303380.1  Ecdysone-induced protein 75B, isoform G [Drosophila melanogaster]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0S0WIG6
    Related
    FBpp0312446, FBtr0347013
    Conserved Domains (2) summary
    cd06940
    Location:188375
    NR_LBD_REV_ERB; The ligand binding domain of REV-ERB receptors, members of the nuclear receptor superfamily
    cd07166
    Location:32120
    NR_DBD_REV_ERB; DNA-binding domain of REV-ERB receptor-like is composed of two C4-type zinc fingers
  7. NM_168757.1NP_730323.1  Ecdysone-induced protein 75B, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_730323.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P17671
    UniProtKB/TrEMBL
    E3CTP0
    Related
    FBpp0074917, FBtr0075151
    Conserved Domains (1) summary
    cd06940
    Location:103290
    NR_LBD_REV_ERB; The ligand binding domain of REV-ERB receptors, members of the nuclear receptor superfamily
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