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PATE2 prostate and testis expressed 2 [ Homo sapiens (human) ]

Gene ID: 399967, updated on 27-Nov-2024

Summary

Official Symbol
PATE2provided by HGNC
Official Full Name
prostate and testis expressed 2provided by HGNC
Primary source
HGNC:HGNC:32249
See related
Ensembl:ENSG00000196844 AllianceGenome:HGNC:32249
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PATE-M; UNQ3112; C11orf38
Summary
Located in extracellular space. [provided by Alliance of Genome Resources, Nov 2024]
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See PATE2 in Genome Data Viewer
Location:
11q24.2
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (125776113..125778828, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (125804709..125807423, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (125646008..125648723, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105369551 Neighboring gene prostate and testis expressed 1 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:125672677-125673178 Neighboring gene prostate and testis expressed 3 Neighboring gene prostate and testis expressed 4

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

HIV-1 interactions

Replication interactions

Interaction Pubs
Knockdown of prostate and testis expressed 2 (PATE2) by siRNA enhances the early stages of HIV-1 replication in HeLa-CD4 cells infected with viral pseudotypes HIV89.6R and HIV8.2N PubMed

Go to the HIV-1, Human Interaction Database

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
prostate and testis expressed protein 2
Names
LVLF3112
PATE-like protein M
prostate and testis expression M

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_212555.3NP_997720.1  prostate and testis expressed protein 2 precursor

    See identical proteins and their annotated locations for NP_997720.1

    Status: VALIDATED

    Source sequence(s)
    AP003087, AY358105
    Consensus CDS
    CCDS8465.1
    UniProtKB/Swiss-Prot
    B2RNZ2, B7ZMG4, Q6UY27
    Related
    ENSP00000351325.3, ENST00000358524.8

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    125776113..125778828 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    125804709..125807423 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)