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MIR100HG mir-100-let-7a-2-mir-125b-1 cluster host gene [ Homo sapiens (human) ]

Gene ID: 399959, updated on 19-Jul-2022

Summary

Official Symbol
MIR100HGprovided by HGNC
Official Full Name
mir-100-let-7a-2-mir-125b-1 cluster host geneprovided by HGNC
Primary source
HGNC:HGNC:39522
See related
Ensembl:ENSG00000255248 MIM:615965; AllianceGenome:HGNC:39522
Gene type
ncRNA
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
AGD1; lncRNA-N2; linc-NeD125
Summary
This gene produces long non-coding RNAs that act as regulators of cell proliferation. Alternative promoter usage and splicing results in multiple transcript variants. Some transcript variants may promote growth, while others may act to negatively regulate cell division. [provided by RefSeq, May 2016]
Expression
Broad expression in ovary (RPKM 32.2), gall bladder (RPKM 20.3) and 18 other tissues See more
Orthologs
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Genomic context

See MIR100HG in Genome Data Viewer
Location:
11q24.1
Exon count:
17
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (122028329..122422871, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (122057374..122452245, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (121899037..122293579, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene VISTA enhancer hs872 Neighboring gene RNA, U6 small nuclear 256, pseudogene Neighboring gene microRNA 125b-1 Neighboring gene microRNA let-7a-2 Neighboring gene BH3-like motif containing, cell death inducer Neighboring gene microRNA 10526 Neighboring gene microRNA 100 Neighboring gene RNA, U4atac small nuclear 10, pseudogene Neighboring gene RNA, U4atac small nuclear 5, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

EBI GWAS Catalog

Description
A genome-wide association analysis identified a novel susceptible locus for pathological myopia at 11q24.1.
EBI GWAS Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Other Names

  • adipogenesis down-regulated transcript 1
  • lncRNA neuronal 2
  • mir-100-let-7a-2 cluster host gene (non-protein coding)
  • neuronal differentiation lncRNA hosting miR-125

Clone Names

  • FLJ11490, FLJ18351, FLJ34394, FLJ41953, DKFZp686L0115, DKFZp686J24156

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_024430.2 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) is the reference variant.
    Source sequence(s)
    AK311309, AP000755, AP001924
  2. NR_137175.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) represents use of an alternate promoter compared to variant 1.
    Source sequence(s)
    AP001924
    Related
    ENST00000529823.2
  3. NR_137176.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3, also known as linc-NeD125) represents use of an alternate promoter compared to variant 1.
    Source sequence(s)
    AP001924, BC040599, BX538058
  4. NR_137177.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) represents use of an alternate promoter compared to variant 1.
    Source sequence(s)
    AP001924, BC040599, BX538058, BX647608
    Related
    ENST00000524376.2
  5. NR_137178.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) represents use of an alternate promoter, differs in the 5' and 3' exon structure, and is shorter than variant 1.
    Source sequence(s)
    AP001924, BC089451
  6. NR_137179.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6) represents use of an alternate promoter compared to variant 1.
    Source sequence(s)
    AP001924, DA861327
  7. NR_137180.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (7) represents use of an alternate promoter compared to variant 1.
    Source sequence(s)
    AP001924, DA788103, DA808613
  8. NR_137181.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AP000755, AP001924, DA153922
  9. NR_137182.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AB485963, AP000755, AP001924
    Related
    ENST00000664908.1
  10. NR_137183.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (10) represents use of an alternate promoter compared to variant 1.
    Source sequence(s)
    AP001924, DA474693, DA650430
    Related
    ENST00000656793.1
  11. NR_137184.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (11) represents use of an alternate promoter compared to variant 1.
    Source sequence(s)
    AP001924, DA474693, DA659486
  12. NR_137185.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (12) represents use of an alternate promoter compared to variant 1.
    Source sequence(s)
    AP001924, DA474693, DA649890
  13. NR_137186.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (13) represents use of an alternate promoter compared to variant 1.
    Source sequence(s)
    AP001924, DA597554
    Related
    ENST00000660603.1
  14. NR_137187.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (14) represents use of an alternate promoter compared to variant 1.
    Source sequence(s)
    AP001924, DA027094, DA597554
    Related
    ENST00000648209.1
  15. NR_137188.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (15) represents use of an alternate promoter compared to variant 1.
    Source sequence(s)
    AP001359, AP001924, DA349788
    Related
    ENST00000650497.1
  16. NR_137189.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (16) represents use of an alternate promoter compared to variant 1.
    Source sequence(s)
    AP001924, DA769636
    Related
    ENST00000654519.1
  17. NR_137190.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (17) represents use of an alternate promoter compared to variant 1.
    Source sequence(s)
    AP001924, DA532588
    Related
    ENST00000531071.6
  18. NR_137191.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (18) represents use of an alternate promoter compared to variant 1.
    Source sequence(s)
    AP001924, DB248200
    Related
    ENST00000532890.6
  19. NR_137192.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (19) represents use of an alternate promoter compared to variant 1.
    Source sequence(s)
    AP000755, AP001359, AP001835, AP001924
    Related
    ENST00000661848.1
  20. NR_137193.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (20) represents use of an alternate promoter compared to variant 1.
    Source sequence(s)
    AP000755, AP001359, AP001924, KF459774
    Related
    ENST00000662950.1
  21. NR_137194.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (21) represents use of an alternate promoter compared to variant 1.
    Source sequence(s)
    AP001359, AP001924, KF459774
    Related
    ENST00000663296.1
  22. NR_137195.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (22) represents use of an alternate promoter compared to variant 1.
    Source sequence(s)
    AP001924
    Related
    ENST00000658364.1
  23. NR_137196.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (23) represents use of an alternate promoter compared to variant 1.
    Source sequence(s)
    AP001924
    Related
    ENST00000653167.1

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    122028329..122422871 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    122057374..122452245 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)