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CTXN2 cortexin 2 [ Homo sapiens (human) ]

Gene ID: 399697, updated on 10-Oct-2023

Summary

Official Symbol
CTXN2provided by HGNC
Official Full Name
cortexin 2provided by HGNC
Primary source
HGNC:HGNC:31109
See related
Ensembl:ENSG00000233932 AllianceGenome:HGNC:31109
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See CTXN2 in Genome Data Viewer
Location:
15q21.1
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 15 NC_000015.10 (48178438..48203758)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 15 NC_060939.1 (45986536..46011849)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (48470635..48495955)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124903485 Neighboring gene solute carrier family 24 member 5 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr15:48442018-48442582 Neighboring gene myelin expression factor 2 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6412 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6413 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr15:48470436-48471087 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:48483866-48484369 Neighboring gene CTXN2 antisense RNA 1 Neighboring gene solute carrier family 12 member 1 Neighboring gene uncharacterized LOC128966560 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr15:48543423-48544622 Neighboring gene MPRA-validated peak2328 silencer Neighboring gene uncharacterized LOC124903486 Neighboring gene DUT antisense RNA 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001145668.2NP_001139140.1  cortexin-2

    See identical proteins and their annotated locations for NP_001139140.1

    Status: VALIDATED

    Source sequence(s)
    AC066612, BX537772
    Consensus CDS
    CCDS45254.1
    UniProtKB/Swiss-Prot
    P0C2S0
    Related
    ENSP00000406145.2, ENST00000417307.3
    Conserved Domains (1) summary
    pfam11057
    Location:981
    Cortexin; Cortexin of kidney
  2. NM_001370415.1NP_001357344.1  cortexin-2

    Status: VALIDATED

    Source sequence(s)
    AC066612
    Consensus CDS
    CCDS45254.1
    UniProtKB/Swiss-Prot
    P0C2S0
    Related
    ENSP00000495979.1, ENST00000645050.1
    Conserved Domains (1) summary
    pfam11057
    Location:981
    Cortexin; Cortexin of kidney
  3. NM_001370416.1NP_001357345.1  cortexin-2

    Status: VALIDATED

    Source sequence(s)
    AC066612
    Consensus CDS
    CCDS45254.1
    UniProtKB/Swiss-Prot
    P0C2S0
    Related
    ENSP00000493942.1, ENST00000647363.1
    Conserved Domains (1) summary
    pfam11057
    Location:981
    Cortexin; Cortexin of kidney

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p14 Primary Assembly

    Range
    48178438..48203758
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047432494.1XP_047288450.1  cortexin-2 isoform X1

    UniProtKB/Swiss-Prot
    P0C2S0
    Related
    ENSP00000495988.1, ENST00000644354.1
  2. XM_017022178.2XP_016877667.1  cortexin-2 isoform X1

    UniProtKB/Swiss-Prot
    P0C2S0
    Conserved Domains (1) summary
    pfam11057
    Location:981
    Cortexin; Cortexin of kidney
  3. XM_006720504.3XP_006720567.1  cortexin-2 isoform X1

    See identical proteins and their annotated locations for XP_006720567.1

    UniProtKB/Swiss-Prot
    P0C2S0
    Conserved Domains (1) summary
    pfam11057
    Location:981
    Cortexin; Cortexin of kidney

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060939.1 Alternate T2T-CHM13v2.0

    Range
    45986536..46011849
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054377899.1XP_054233874.1  cortexin-2 isoform X1

    UniProtKB/Swiss-Prot
    P0C2S0
  2. XM_054377898.1XP_054233873.1  cortexin-2 isoform X1

    UniProtKB/Swiss-Prot
    P0C2S0
  3. XM_054377900.1XP_054233875.1  cortexin-2 isoform X1

    UniProtKB/Swiss-Prot
    P0C2S0