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hao2.L hydroxyacid oxidase 2 (long chain) L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 398510, updated on 4-Jan-2025

Summary

Official Symbol
hao2.L
Official Full Name
hydroxyacid oxidase 2 (long chain) L homeolog
Primary source
Xenbase:XB-GENE-17333925
Locus tag
XELAEV_18011251mg
See related
EnsemblRapid:ENSXLAG00005025272 AllianceGenome:Xenbase:XB-GENE-17333925
Gene type
protein coding
RefSeq status
PREDICTED
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Summary
Predicted to enable FMN binding activity and oxidoreductase activity. Predicted to be located in peroxisome. Orthologous to human HAO2 (hydroxyacid oxidase 2). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

See hao2.L in Genome Data Viewer
Location:
chromosome: 2L
Exon count:
9
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 2L NC_054373.1 (1500345..1517189, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 2L NC_030726.1 (1500621..1517461, complement)

Chromosome 2L - NC_054373.1Genomic Context describing neighboring genes Neighboring gene phospholipase A1 member A L homeolog Neighboring gene hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 L homeolog Neighboring gene tryptophanyl tRNA synthetase 2, mitochondrial L homeolog Neighboring gene T-box 15 L homeolog Neighboring gene uncharacterized LOC121399789

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables FMN binding IEA
Inferred from Electronic Annotation
more info
 
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in peroxisome IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
uncharacterized protein LOC398510

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001089031.2NP_001082500.1  uncharacterized protein LOC398510

    See identical proteins and their annotated locations for NP_001082500.1

    Status: PREDICTED

    Source sequence(s)
    BC073662
    UniProtKB/TrEMBL
    A0A974HXA5, Q6GN56
    Related
    ENSXLAP00005075297.1, ENSXLAT00005076877.1
    Conserved Domains (2) summary
    cd02809
    Location:7348
    alpha_hydroxyacid_oxid_FMN; Family of homologous FMN-dependent alpha-hydroxyacid oxidizing enzymes. This family occurs in both prokaryotes and eukaryotes. Members of this family include flavocytochrome b2 (FCB2), glycolate oxidase (GOX), lactate monooxygenase (LMO), mandelate ...
    pfam01070
    Location:14352
    FMN_dh; FMN-dependent dehydrogenase

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054373.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    1500345..1517189 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018244886.2XP_018100375.1  uncharacterized protein LOC398510 isoform X3

    UniProtKB/TrEMBL
    A0A8J0UAG4, A0A974HXA5
    Related
    ENSXLAP00005075551.1, ENSXLAT00005077131.1
    Conserved Domains (1) summary
    pfam01070
    Location:13352
    FMN_dh; FMN-dependent dehydrogenase
  2. XM_041580910.1XP_041436844.1  uncharacterized protein LOC398510 isoform X3

    UniProtKB/TrEMBL
    A0A8J0UAG4, A0A974HXA5
    Conserved Domains (1) summary
    pfam01070
    Location:13352
    FMN_dh; FMN-dependent dehydrogenase
  3. XM_018244883.2XP_018100372.1  uncharacterized protein LOC398510 isoform X2

    UniProtKB/TrEMBL
    A0A8J0UBN7, A0A974HXA5
    Related
    ENSXLAP00005075408.1, ENSXLAT00005076988.1
  4. XM_018244887.2XP_018100376.1  uncharacterized protein LOC398510 isoform X4

    UniProtKB/TrEMBL
    A0A8J0UBS5, A0A974HXA5
    Related
    ENSXLAP00005075327.1, ENSXLAT00005076908.1
  5. XM_018244885.2XP_018100374.2  uncharacterized protein LOC398510 isoform X1

    UniProtKB/TrEMBL
    A0A8J0U3I2, A0A974HXA5
    Conserved Domains (1) summary
    cd02809
    Location:48389
    alpha_hydroxyacid_oxid_FMN; Family of homologous FMN-dependent alpha-hydroxyacid oxidizing enzymes. This family occurs in both prokaryotes and eukaryotes. Members of this family include flavocytochrome b2 (FCB2), glycolate oxidase (GOX), lactate monooxygenase (LMO), mandelate ...