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ABLIM1 actin binding LIM protein 1 [ Homo sapiens (human) ]

Gene ID: 3983, updated on 2-Oct-2018

Summary

Official Symbol
ABLIM1provided by HGNC
Official Full Name
actin binding LIM protein 1provided by HGNC
Primary source
HGNC:HGNC:78
See related
Ensembl:ENSG00000099204 MIM:602330; Vega:OTTHUMG00000019088
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ABLIM; LIMAB1; LIMATIN; abLIM-1
Summary
This gene encodes a LIM zinc-binding domain-containing protein that binds to actin filaments and mediates interactions between actin and cytoplasmic targets. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jun 2017]
Expression
Ubiquitous expression in ovary (RPKM 50.7), heart (RPKM 50.1) and 23 other tissues See more
Orthologs

Genomic context

See ABLIM1 in Genome Data Viewer
Location:
10q25.3
Exon count:
33
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 10 NC_000010.11 (114431110..114821643, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (116190869..116444762, complement)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105378494 Neighboring gene actin filament associated protein 1 like 2 Neighboring gene RNA, 7SL, cytoplasmic 384, pseudogene Neighboring gene peptidylprolyl isomerase A pseudogene 19 Neighboring gene uncharacterized LOC101927692 Neighboring gene TATA-box binding protein associated factor 9b pseudogene 2 Neighboring gene family with sequence similarity 160 member B1 Neighboring gene ribosomal protein L15 pseudogene 13

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Phenotypes

NHGRI GWAS Catalog

Description
A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.
NHGRI GWA Catalog
Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
NHGRI GWA Catalog

Pathways from BioSystems

  • Axon guidance, organism-specific biosystem (from KEGG)
    Axon guidance, organism-specific biosystemAxon guidance represents a key stage in the formation of neuronal network. Axons are guided by a variety of guidance factors, such as netrins, ephrins, Slits, and semaphorins. These guidance cues are...
  • Axon guidance, conserved biosystem (from KEGG)
    Axon guidance, conserved biosystemAxon guidance represents a key stage in the formation of neuronal network. Axons are guided by a variety of guidance factors, such as netrins, ephrins, Slits, and semaphorins. These guidance cues are...
  • Axon guidance, organism-specific biosystem (from REACTOME)
    Axon guidance, organism-specific biosystemAxon guidance / axon pathfinding is the process by which neurons send out axons to reach the correct targets. Growing axons have a highly motile structure at the growing tip called the growth cone, w...
  • DCC mediated attractive signaling, organism-specific biosystem (from REACTOME)
    DCC mediated attractive signaling, organism-specific biosystemThe DCC family includes DCC and neogenin in vertebrates. DCC is required for netrin-induced axon attraction. DCC is a transmembrane protein lacking any identifiable catalytic activity. Protein tyrosi...
  • Developmental Biology, organism-specific biosystem (from REACTOME)
    Developmental Biology, organism-specific biosystemAs a first step towards capturing the array of processes by which a fertilized egg gives rise to the diverse tissues of the body, examples of three kinds of processes have been annotated. These are a...
  • Netrin-1 signaling, organism-specific biosystem (from REACTOME)
    Netrin-1 signaling, organism-specific biosystemNetrins are secreted proteins that play a crucial role in neuronal migration and in axon guidance during the development of the nervous system. To date, several Netrins have been described in mouse a...

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC1224, FLJ14564, KIAA0059, DKFZp781D0148

Gene Ontology Provided by GOA

Function Evidence Code Pubs
actin binding TAS
Traceable Author Statement
more info
PubMed 
actin filament binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
animal organ morphogenesis TAS
Traceable Author Statement
more info
PubMed 
cilium assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cilium assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 
lamellipodium assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
lamellipodium assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
visual perception TAS
Traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
actin cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
lamellipodium IDA
Inferred from Direct Assay
more info
PubMed 
stress fiber IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
stress fiber IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
actin-binding LIM protein 1
Names
actin-binding LIM protein family member 1
actin-binding double-zinc-finger protein

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_029872.2 RefSeqGene

    Range
    141989..395534
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001003407.1NP_001003407.1  actin-binding LIM protein 1 isoform b

    See identical proteins and their annotated locations for NP_001003407.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and the 5' coding region, compared to variant 1. The resulting isoform (b) contains a distinct N-terminus, compared to isoform a.
    Source sequence(s)
    AL133384, AL354873, AW627433, D31883
    Consensus CDS
    CCDS31288.1
    UniProtKB/Swiss-Prot
    O14639
    Related
    ENSP00000376682.4, OTTHUMP00000020531, ENST00000392955.7, OTTHUMT00000050470
    Conserved Domains (7) summary
    smart00153
    Location:683718
    VHP; Villin headpiece domain
    cd09327
    Location:3990
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:95150
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:166217
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:225280
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam16182
    Location:290682
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
    cl14106
    Location:520580
    Rifin_STEVOR; Rifin/stevor family
  2. NM_001322882.2NP_001309811.1  actin-binding LIM protein 1 isoform d

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) represents the longest transcript and differs in the 5' UTR and 5' coding region compared to variant 1. The encoded isoform (d) has a shorter, distinct N-terminus compared to isoform a.
    Source sequence(s)
    AK122891, AL133384, AL354873
    Consensus CDS
    CCDS81509.1
    UniProtKB/Swiss-Prot
    O14639
    Related
    ENSP00000358260.3, OTTHUMP00000272285, ENST00000369256.6
    Conserved Domains (7) summary
    smart00153
    Location:713748
    VHP; Villin headpiece domain
    cd09327
    Location:3990
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:95150
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:166217
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:225280
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam16182
    Location:318712
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
    cl14106
    Location:550610
    Rifin_STEVOR; Rifin/stevor family
  3. NM_001322883.1NP_001309812.1  actin-binding LIM protein 1 isoform e

    Status: REVIEWED

    Source sequence(s)
    AL133384, AL354873
  4. NM_001322884.2NP_001309813.1  actin-binding LIM protein 1 isoform f

    Status: REVIEWED

    Source sequence(s)
    AL133384, AL137025, AL354873
  5. NM_001322885.2NP_001309814.1  actin-binding LIM protein 1 isoform g

    Status: REVIEWED

    Source sequence(s)
    AL133384, AL137025, AL354873
  6. NM_001322886.2NP_001309815.1  actin-binding LIM protein 1 isoform h

    Status: REVIEWED

    Source sequence(s)
    AL133384, AL137025, AL354873
  7. NM_001322887.1NP_001309816.1  actin-binding LIM protein 1 isoform i

    Status: REVIEWED

    Source sequence(s)
    AL133384, AL354873
  8. NM_001322888.1NP_001309817.1  actin-binding LIM protein 1 isoform j

    Status: REVIEWED

    Source sequence(s)
    AL133384
  9. NM_001322889.1NP_001309818.1  actin-binding LIM protein 1 isoform k

    Status: REVIEWED

    Source sequence(s)
    AL133384
  10. NM_001322890.1NP_001309819.1  actin-binding LIM protein 1 isoform l

    Status: REVIEWED

    Description
    Transcript Variant: This variant (13) and variant 14 both encode isoform l.
    Source sequence(s)
    AL133384
    Conserved Domains (4) summary
    smart00153
    Location:394429
    VHP; Villin headpiece domain
    pfam16182
    Location:34393
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
    cl02475
    Location:124
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    cl14106
    Location:231291
    Rifin_STEVOR; Rifin/stevor family
  11. NM_001322891.1NP_001309820.1  actin-binding LIM protein 1 isoform l

    Status: REVIEWED

    Description
    Transcript Variant: This variant (14) and variant 13 both encode isoform l.
    Source sequence(s)
    AL133384
    Conserved Domains (4) summary
    smart00153
    Location:394429
    VHP; Villin headpiece domain
    pfam16182
    Location:34393
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
    cl02475
    Location:124
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    cl14106
    Location:231291
    Rifin_STEVOR; Rifin/stevor family
  12. NM_001322892.1NP_001309821.1  actin-binding LIM protein 1 isoform n

    Status: REVIEWED

    Description
    Transcript Variant: This variant (15) and variant 16 both encode isoform n.
    Source sequence(s)
    AL133384
    UniProtKB/Swiss-Prot
    O14639
    Conserved Domains (4) summary
    smart00153
    Location:392427
    VHP; Villin headpiece domain
    pfam16182
    Location:34391
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
    cl02475
    Location:124
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    cl14106
    Location:229289
    Rifin_STEVOR; Rifin/stevor family
  13. NM_001322893.1NP_001309822.1  actin-binding LIM protein 1 isoform n

    Status: REVIEWED

    Description
    Transcript Variant: This variant (16) and variant 15 both encode isoform n.
    Source sequence(s)
    AL133384
    UniProtKB/Swiss-Prot
    O14639
    Conserved Domains (4) summary
    smart00153
    Location:392427
    VHP; Villin headpiece domain
    pfam16182
    Location:34391
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
    cl02475
    Location:124
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    cl14106
    Location:229289
    Rifin_STEVOR; Rifin/stevor family
  14. NM_001322894.1NP_001309823.1  actin-binding LIM protein 1 isoform o

    Status: REVIEWED

    Description
    Transcript Variant: This variant (17) and variant 18 both encode isoform o.
    Source sequence(s)
    AL133384
  15. NM_001322895.1NP_001309824.1  actin-binding LIM protein 1 isoform o

    Status: REVIEWED

    Description
    Transcript Variant: This variant (18) and variant 17 both encode isoform o.
    Source sequence(s)
    AL133384
  16. NM_001322896.1NP_001309825.1  actin-binding LIM protein 1 isoform p

    Status: REVIEWED

    Source sequence(s)
    AL133384, BC002448
    Consensus CDS
    CCDS81508.1
    UniProtKB/Swiss-Prot
    O14639
    Related
    ENSP00000358257.2, OTTHUMP00000020537, ENST00000369253.6, OTTHUMT00000050478
    Conserved Domains (2) summary
    smart00153
    Location:366401
    VHP; Villin headpiece domain
    pfam16182
    Location:8365
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  17. NM_001322897.1NP_001309826.1  actin-binding LIM protein 1 isoform q

    Status: REVIEWED

    Source sequence(s)
    AL133384
    Conserved Domains (2) summary
    smart00153
    Location:354389
    VHP; Villin headpiece domain
    pfam16182
    Location:8353
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  18. NM_001322898.1NP_001309827.1  actin-binding LIM protein 1 isoform r

    Status: REVIEWED

    Description
    Transcript Variant: This variant (21) and variant 22 both encode isoform r.
    Source sequence(s)
    AL133384
    UniProtKB/TrEMBL
    B4DQA3
    Conserved Domains (3) summary
    smart00153
    Location:345380
    VHP; Villin headpiece domain
    pfam16182
    Location:34344
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
    cl02475
    Location:124
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
  19. NM_001322899.1NP_001309828.1  actin-binding LIM protein 1 isoform r

    Status: REVIEWED

    Description
    Transcript Variant: This variant (22) and variant 21 both encode isoform r.
    Source sequence(s)
    AL133384
    UniProtKB/TrEMBL
    B4DQA3
    Conserved Domains (3) summary
    smart00153
    Location:345380
    VHP; Villin headpiece domain
    pfam16182
    Location:34344
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
    cl02475
    Location:124
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
  20. NM_001322900.1NP_001309829.1  actin-binding LIM protein 1 isoform t

    Status: REVIEWED

    Source sequence(s)
    AL133384
    Conserved Domains (2) summary
    smart00153
    Location:319354
    VHP; Villin headpiece domain
    pfam16182
    Location:8318
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  21. NM_001352440.1NP_001339369.1  actin-binding LIM protein 1 isoform u

    Status: REVIEWED

    Source sequence(s)
    AK297344, AL133384, AL354873, DC376979
    Conserved Domains (6) summary
    smart00153
    Location:620655
    VHP; Villin headpiece domain
    cd09327
    Location:2374
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:79134
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:150201
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:209264
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam16182
    Location:274619
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  22. NM_001352441.1NP_001339370.1  actin-binding LIM protein 1 isoform v

    Status: REVIEWED

    Source sequence(s)
    AL133384, AL354873, DC376979
    Conserved Domains (6) summary
    smart00153
    Location:585620
    VHP; Villin headpiece domain
    cd09327
    Location:2374
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:79134
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:150201
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:209264
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam16182
    Location:274584
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  23. NM_001352442.1NP_001339371.1  actin-binding LIM protein 1 isoform w

    Status: REVIEWED

    Source sequence(s)
    AK093471, AL133384, AL354873, DB039901
    Conserved Domains (5) summary
    smart00153
    Location:556591
    VHP; Villin headpiece domain
    cd09328
    Location:358
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:74125
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:133188
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam16182
    Location:198555
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  24. NM_001352443.1NP_001339372.1  actin-binding LIM protein 1 isoform x

    Status: REVIEWED

    Source sequence(s)
    AL133384
    Conserved Domains (3) summary
    smart00153
    Location:429464
    VHP; Villin headpiece domain
    cl02475
    Location:124
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    pfam16182
    Location:34428
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  25. NM_002313.6NP_002304.3  actin-binding LIM protein 1 isoform a

    See identical proteins and their annotated locations for NP_002304.3

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (a).
    Source sequence(s)
    AF005654, AL133384, AL354873
    Consensus CDS
    CCDS7590.1
    UniProtKB/Swiss-Prot
    O14639
    Related
    ENSP00000277895.5, OTTHUMP00000020530, ENST00000277895.9
    Conserved Domains (7) summary
    smart00153
    Location:743778
    VHP; Villin headpiece domain
    cd09327
    Location:99150
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:155210
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:226277
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:285340
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam16182
    Location:350742
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
    cl14106
    Location:580640
    Rifin_STEVOR; Rifin/stevor family
  26. NM_006720.3NP_006711.3  actin-binding LIM protein 1 isoform s

    See identical proteins and their annotated locations for NP_006711.3

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) contains a distinct 5' UTR and has multiple differences in the coding region, compared to variant 1. It also uses a downstream start codon, compared to variant 1. The resulting isoform (s) is shorter, compared to isoform a.
    Source sequence(s)
    AI680726, AK058007, AK093471, AK122891, AL600892, AL710059, AW627433, BC002448, BE395092, BE672277, BG426037, BQ721521, CA450184, CB128609, CD558045, D31883
    Consensus CDS
    CCDS31289.1
    UniProtKB/Swiss-Prot
    O14639
    UniProtKB/TrEMBL
    B3KSG3
    Related
    ENSP00000376679.3, OTTHUMP00000020536, ENST00000392952.7, OTTHUMT00000050477
    Conserved Domains (4) summary
    smart00153
    Location:420455
    VHP; Villin headpiece domain
    pfam16182
    Location:62419
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
    cl02475
    Location:124
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    cl14106
    Location:257317
    Rifin_STEVOR; Rifin/stevor family

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p12 Primary Assembly

    Range
    114431110..114821643 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011539805.1XP_011538107.1  actin-binding LIM protein 1 isoform X2

    Conserved Domains (5) summary
    smart00153
    Location:661696
    VHP; Villin headpiece domain
    cd09328
    Location:358
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:74125
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:133188
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam16182
    Location:226660
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  2. XM_017016255.1XP_016871744.1  actin-binding LIM protein 1 isoform X16

  3. XM_017016250.1XP_016871739.1  actin-binding LIM protein 1 isoform X14

  4. XM_017016245.1XP_016871734.1  actin-binding LIM protein 1 isoform X9

  5. XM_006717837.2XP_006717900.1  actin-binding LIM protein 1 isoform X4

    Conserved Domains (6) summary
    smart00153
    Location:753788
    VHP; Villin headpiece domain
    cd09327
    Location:3990
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:95150
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:166217
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:225280
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam16182
    Location:318752
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  6. XM_011539802.2XP_011538104.2  actin-binding LIM protein 1 isoform X6

    Conserved Domains (6) summary
    smart00153
    Location:743778
    VHP; Villin headpiece domain
    cd09327
    Location:2980
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:156207
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:215270
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam16182
    Location:308742
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  7. XM_024448020.1XP_024303788.1  actin-binding LIM protein 1 isoform X20

    Conserved Domains (5) summary
    smart00153
    Location:544579
    VHP; Villin headpiece domain
    cd09328
    Location:358
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:74125
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:133188
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam16182
    Location:198543
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  8. XM_024448021.1XP_024303789.1  actin-binding LIM protein 1 isoform X21

    Conserved Domains (5) summary
    smart00153
    Location:509544
    VHP; Villin headpiece domain
    cd09328
    Location:358
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:74125
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:133188
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam16182
    Location:198508
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  9. XM_017016256.1XP_016871745.1  actin-binding LIM protein 1 isoform X18

  10. XM_024448016.1XP_024303784.1  actin-binding LIM protein 1 isoform X13

    Conserved Domains (6) summary
    smart00153
    Location:709744
    VHP; Villin headpiece domain
    cd09327
    Location:2374
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:79134
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:150201
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:209264
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam16182
    Location:274708
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  11. XM_024448018.1XP_024303786.1  actin-binding LIM protein 1 isoform X17

    Conserved Domains (6) summary
    smart00153
    Location:662697
    VHP; Villin headpiece domain
    cd09327
    Location:2374
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:79134
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:150201
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:209264
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam16182
    Location:302661
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  12. XM_024448014.1XP_024303782.1  actin-binding LIM protein 1 isoform X8

    Conserved Domains (6) summary
    smart00153
    Location:737772
    VHP; Villin headpiece domain
    cd09327
    Location:2374
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:79134
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:150201
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:209264
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam16182
    Location:302736
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  13. XM_024448013.1XP_024303781.1  actin-binding LIM protein 1 isoform X7

    Conserved Domains (5) summary
    smart00153
    Location:633668
    VHP; Villin headpiece domain
    cd09328
    Location:358
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:74125
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:133188
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam16182
    Location:198632
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  14. XM_011539801.2XP_011538103.2  actin-binding LIM protein 1 isoform X2

    Conserved Domains (5) summary
    smart00153
    Location:661696
    VHP; Villin headpiece domain
    cd09328
    Location:358
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:74125
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:133188
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam16182
    Location:226660
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  15. XM_017016248.1XP_016871737.1  actin-binding LIM protein 1 isoform X11

  16. XM_024448017.1XP_024303785.1  actin-binding LIM protein 1 isoform X15

    Conserved Domains (5) summary
    smart00153
    Location:537572
    VHP; Villin headpiece domain
    cd09328
    Location:358
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:74125
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:133188
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam16182
    Location:226536
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  17. XM_017016247.1XP_016871736.1  actin-binding LIM protein 1 isoform X10

  18. XM_024448015.1XP_024303783.1  actin-binding LIM protein 1 isoform X12

    Conserved Domains (5) summary
    smart00153
    Location:572607
    VHP; Villin headpiece domain
    cd09328
    Location:358
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:74125
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:133188
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam16182
    Location:226571
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  19. XM_024448011.1XP_024303779.1  actin-binding LIM protein 1 isoform X3

    Conserved Domains (5) summary
    smart00153
    Location:619654
    VHP; Villin headpiece domain
    cd09328
    Location:358
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:74125
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:133188
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam16182
    Location:226618
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  20. XM_024448012.1XP_024303780.1  actin-binding LIM protein 1 isoform X5

    Conserved Domains (5) summary
    smart00153
    Location:612647
    VHP; Villin headpiece domain
    cd09328
    Location:358
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:74125
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:133188
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam16182
    Location:226611
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  21. XM_024448010.1XP_024303778.1  actin-binding LIM protein 1 isoform X1

    Conserved Domains (5) summary
    smart00153
    Location:659694
    VHP; Villin headpiece domain
    cd09328
    Location:358
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:74125
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:133188
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam16182
    Location:226658
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  22. XM_024448022.1XP_024303790.1  actin-binding LIM protein 1 isoform X25

    Conserved Domains (3) summary
    smart00153
    Location:427462
    VHP; Villin headpiece domain
    cl02475
    Location:124
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    pfam16182
    Location:34426
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  23. XM_005269827.4XP_005269884.1  actin-binding LIM protein 1 isoform X23

    See identical proteins and their annotated locations for XP_005269884.1

    Conserved Domains (4) summary
    smart00153
    Location:469504
    VHP; Villin headpiece domain
    pfam16182
    Location:34468
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
    cl02475
    Location:124
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    cl14106
    Location:306366
    Rifin_STEVOR; Rifin/stevor family
  24. XM_006717846.3XP_006717909.1  actin-binding LIM protein 1 isoform X22

    See identical proteins and their annotated locations for XP_006717909.1

    Conserved Domains (4) summary
    smart00153
    Location:497532
    VHP; Villin headpiece domain
    pfam16182
    Location:62496
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
    cl02475
    Location:124
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    cl14106
    Location:334394
    Rifin_STEVOR; Rifin/stevor family
  25. XM_005269826.1XP_005269883.1  actin-binding LIM protein 1 isoform X22

    See identical proteins and their annotated locations for XP_005269883.1

    Conserved Domains (4) summary
    smart00153
    Location:497532
    VHP; Villin headpiece domain
    pfam16182
    Location:62496
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
    cl02475
    Location:124
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    cl14106
    Location:334394
    Rifin_STEVOR; Rifin/stevor family
  26. XM_017016259.1XP_016871748.1  actin-binding LIM protein 1 isoform X24

    Conserved Domains (3) summary
    smart00153
    Location:429464
    VHP; Villin headpiece domain
    cl02475
    Location:124
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    pfam16182
    Location:34428
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  27. XM_006717847.1XP_006717910.1  actin-binding LIM protein 1 isoform X23

    See identical proteins and their annotated locations for XP_006717910.1

    Conserved Domains (4) summary
    smart00153
    Location:469504
    VHP; Villin headpiece domain
    pfam16182
    Location:34468
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
    cl02475
    Location:124
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    cl14106
    Location:306366
    Rifin_STEVOR; Rifin/stevor family
  28. XM_024448019.1XP_024303787.1  actin-binding LIM protein 1 isoform X19

    Conserved Domains (4) summary
    cd09328
    Location:358
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:74125
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:133188
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam16182
    Location:226451
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001003408.1: Suppressed sequence

    Description
    NM_001003408.1: This RefSeq was removed because currently there is insufficient support for the transcript and protein.
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