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KCNJ2 potassium inwardly rectifying channel subfamily J member 2 [ Sus scrofa (pig) ]

Gene ID: 397293, updated on 5-Mar-2024

Summary

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Official Symbol
KCNJ2provided by VGNC
Official Full Name
potassium inwardly rectifying channel subfamily J member 2provided by VGNC
Primary source
VGNC:VGNC:89357
See related
Ensembl:ENSSSCG00000039947
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Also known as
IRK1
Expression
Broad expression in heart (RPKM 7.2), psoas major muscle (RPKM 3.0) and 5 other tissues See more
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 12
Exon count:
7
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 12 NC_010454.4 (10351959..10380631, complement)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) Unplaced Scaffold NW_003612993.1 (92222..93638, complement)

Chromosome 12 - NC_010454.4Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102165790 Neighboring gene uncharacterized LOC110255978 Neighboring gene uncharacterized LOC110255979 Neighboring gene uncharacterized LOC102166398 Neighboring gene potassium inwardly rectifying channel subfamily J member 16 Neighboring gene uncharacterized LOC106505399 Neighboring gene mitogen-activated protein kinase kinase 6

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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Related articles in PubMed

  1. Inwardly rectifying potassium channels in lens epithelium are from the IRK1 (Kir 2.1) family. Rae JL, et al. Exp Eye Res, 1998 Mar. PMID 9533862

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables inward rectifier potassium channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in potassium ion import across plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of monoatomic ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
inward rectifier potassium channel 2
Names
IRK-1
inward rectifier K(+) channel Kir2.1
potassium channel, inwardly rectifying subfamily J member 2
potassium voltage-gated channel subfamily J member 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_214151.1 → NP_999316.1  inward rectifier potassium channel 2

    See identical proteins and their annotated locations for NP_999316.1

    Status: PROVISIONAL

    Source sequence(s)
    AF021140
    UniProtKB/Swiss-Prot
    O18839
    UniProtKB/TrEMBL
    A0A4X1SLV8
    Conserved Domains (2) summary
    pfam01007
    Location:48 → 373
    IRK; Inward rectifier potassium channel
    pfam08466
    Location:2 → 47
    IRK_N; Inward rectifier potassium channel N-terminal

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010454.4 Reference Sscrofa11.1 Primary Assembly

    Range
    10351959..10380631 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021066223.1 → XP_020921882.1  inward rectifier potassium channel 2 isoform X1

    UniProtKB/Swiss-Prot
    O18839
    UniProtKB/TrEMBL
    A0A4X1SLV8
    Conserved Domains (2) summary
    pfam01007
    Location:48 → 373
    IRK; Inward rectifier potassium channel
    pfam08466
    Location:2 → 47
    IRK_N; Inward rectifier potassium channel N-terminal

  2. XM_021066222.1 → XP_020921881.1  inward rectifier potassium channel 2 isoform X1

    UniProtKB/Swiss-Prot
    O18839
    UniProtKB/TrEMBL
    A0A4X1SLV8
    Conserved Domains (2) summary
    pfam01007
    Location:48 → 373
    IRK; Inward rectifier potassium channel
    pfam08466
    Location:2 → 47
    IRK_N; Inward rectifier potassium channel N-terminal

  3. XM_021066224.1 → XP_020921883.1  inward rectifier potassium channel 2 isoform X1

    UniProtKB/Swiss-Prot
    O18839
    UniProtKB/TrEMBL
    A0A4X1SLV8
    Conserved Domains (2) summary
    pfam01007
    Location:48 → 373
    IRK; Inward rectifier potassium channel
    pfam08466
    Location:2 → 47
    IRK_N; Inward rectifier potassium channel N-terminal

  4. XM_021066221.1 → XP_020921880.1  inward rectifier potassium channel 2 isoform X1

    UniProtKB/Swiss-Prot
    O18839
    UniProtKB/TrEMBL
    A0A4X1SLV8
    Conserved Domains (2) summary
    pfam01007
    Location:48 → 373
    IRK; Inward rectifier potassium channel
    pfam08466
    Location:2 → 47
    IRK_N; Inward rectifier potassium channel N-terminal

  5. XM_021066219.1 → XP_020921878.1  inward rectifier potassium channel 2 isoform X1

    UniProtKB/Swiss-Prot
    O18839
    UniProtKB/TrEMBL
    A0A4X1SLV8
    Related
    ENSSSCP00000043274.1, ENSSSCT00000061811.3
    Conserved Domains (2) summary
    pfam01007
    Location:48 → 373
    IRK; Inward rectifier potassium channel
    pfam08466
    Location:2 → 47
    IRK_N; Inward rectifier potassium channel N-terminal

  6. XM_021066220.1 → XP_020921879.1  inward rectifier potassium channel 2 isoform X1

    UniProtKB/Swiss-Prot
    O18839
    UniProtKB/TrEMBL
    A0A4X1SLV8
    Related
    ENSSSCP00000058999.1, ENSSSCT00000050128.3
    Conserved Domains (2) summary
    pfam01007
    Location:48 → 373
    IRK; Inward rectifier potassium channel
    pfam08466
    Location:2 → 47
    IRK_N; Inward rectifier potassium channel N-terminal
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O18839.1 GenPept UniProtKB/Swiss-Prot:O18839

Gene LinkOut

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