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MYH2 myosin, heavy chain 2, skeletal muscle, adult [ Sus scrofa (pig) ]

Gene ID: 397256, updated on 31-Jul-2024

Summary

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Gene symbol
MYH2
Gene description
myosin, heavy chain 2, skeletal muscle, adult
See related
Ensembl:ENSSSCG00000029441
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression
Biased expression in psoas major muscle (RPKM 1702.2), longissimus dorsi muscle (RPKM 1223.1) and 1 other tissue See more
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Genomic context

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See MYH2 in Genome Data Viewer
Location:
chromosome: 12
Exon count:
41
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 12 NC_010454.4 (55252974..55278820, complement)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 12 NC_010454.3 (58205953..58230234)

Chromosome 12 - NC_010454.4Genomic Context describing neighboring genes Neighboring gene myosin, heavy chain 4, skeletal muscle Neighboring gene myosin, heavy chain 1, skeletal muscle, adult Neighboring gene myosin heavy chain 3 Neighboring gene synthesis of cytochrome C oxidase 1 Neighboring gene ADP-ribose/CDP-alcohol diphosphatase, manganese dependent

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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Related articles in PubMed

  1. Molecular characterization of a developmentally regulated porcine skeletal myosin heavy chain gene and its 5' regulatory region. Chang KC, et al. J Cell Sci, 1995 Apr. PMID 7615692
  2. Differences in molecular structure among the porcine myosin heavy chain-2a, -2x, and -2b isoforms. Chikuni K, et al. Meat Sci, 2001 Mar. PMID 22061506
  3. Porcine myosin-VI: characterization of a new mammalian unconventional myosin. Hasson T, et al. J Cell Biol, 1994 Oct. PMID 7929586, Free PMC Article
  4. PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. Uenishi H, et al. Nucleic Acids Res, 2007 Jan. PMID 17145712, Free PMC Article
  5. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables actin filament binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cytoskeletal motor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of myosin complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
myosin-2
Names
fast myosin heavy chain
myHC-2a
myosin heavy chain 2
myosin heavy chain 2a
myosin heavy chain, skeletal muscle, adult 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_214136.1 → NP_999301.1  myosin-2

    See identical proteins and their annotated locations for NP_999301.1

    Status: PROVISIONAL

    Source sequence(s)
    AB025260
    UniProtKB/Swiss-Prot
    Q9TV63
    UniProtKB/TrEMBL
    A0A8D1T9C0, A0A8D1UCG7
    Related
    ENSSSCP00000019078.3, ENSSSCT00000019597.5
    Conserved Domains (6) summary
    cl22853
    Location:100 → 770
    Motor_domain; Myosin and Kinesin motor domain
    pfam00063
    Location:88 → 770
    Myosin_head; Myosin head (motor domain)
    pfam01576
    Location:850 → 1927
    Myosin_tail_1; Myosin tail
    pfam02736
    Location:36 → 73
    Myosin_N; Myosin N-terminal SH3-like domain
    cl19219
    Location:1670 → 1767
    DUF342; Protein of unknown function (DUF342)
    cl23720
    Location:965 → 1098
    RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010454.4 Reference Sscrofa11.1 Primary Assembly

    Range
    55252974..55278820 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021066217.1 → XP_020921876.1  myosin-2 isoform X1

    UniProtKB/TrEMBL
    A0A4X1SL20, A0A8D1T9C0, A0A8D1UCG7
    Conserved Domains (3) summary
    pfam02736
    Location:35 → 73
    Myosin_N; Myosin N-terminal SH3-like domain
    cl22853
    Location:100 → 770
    Motor_domain; Myosin and Kinesin motor domain
    cl25732
    Location:850 → 1927
    SMC_N; RecF/RecN/SMC N terminal domain

  2. XM_021066216.1 → XP_020921875.1  myosin-2 isoform X1

    UniProtKB/TrEMBL
    A0A4X1SL20, A0A8D1T9C0, A0A8D1UCG7
    Conserved Domains (3) summary
    pfam02736
    Location:35 → 73
    Myosin_N; Myosin N-terminal SH3-like domain
    cl22853
    Location:100 → 770
    Motor_domain; Myosin and Kinesin motor domain
    cl25732
    Location:850 → 1927
    SMC_N; RecF/RecN/SMC N terminal domain
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9TV63.1 GenPept UniProtKB/Swiss-Prot:Q9TV63

Gene LinkOut

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