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LOC396781 IgG heavy chain [ Sus scrofa (pig) ]

Gene ID: 396781, updated on 1-Mar-2025

Summary

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Gene symbol
LOC396781
Gene description
IgG heavy chain
See related
RGD:13963116
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Also known as
IGHG; IGHG1; IGHJ1; IgG1b; IGHG1.02
Expression
Biased expression in spleen (RPKM 979.4), lung (RPKM 342.1) and 1 other tissue See more
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Genomic context

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See LOC396781 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
12
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) Unplaced Scaffold NW_018084979.1 (3676148..3841291, complement)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) Unplaced Scaffold NW_003540947.1 (6..561)

NW_018084979.1Genomic Context describing neighboring genes Neighboring gene immunoglobulin heavy constant alpha 2-like Neighboring gene uncharacterized LOC110258352 Neighboring gene Ig gamma-3 chain C region-like Neighboring gene immunoglobulin heavy constant gamma 4-like Neighboring gene Ig gamma-3 chain C region-like Neighboring gene vegetative cell wall protein gp1-like Neighboring gene immunoglobulin heavy constant gamma 4-like Neighboring gene immunoglobulin heavy constant delta-like Neighboring gene uncharacterized LOC110258350 Neighboring gene disintegrin and metalloproteinase domain-containing protein 20-like Neighboring gene uncharacterized LOC110258351

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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Related articles in PubMed

  1. Five putative subclasses of swine IgG identified from the cDNA sequences of a single animal. Kacskovics I, et al. J Immunol, 1994 Oct 15. PMID 7930579
  2. Porcine reproductive and respiratory syndrome virus subverts repertoire development by proliferation of germline-encoded B cells of all isotypes bearing hydrophobic heavy chain CDR3. Butler JE, et al. J Immunol, 2008 Feb 15. PMID 18250444
  3. Antibody repertoire development in fetal and newborn piglets, III. Colonization of the gastrointestinal tract selectively diversifies the preimmune repertoire in mucosal lymphoid tissues. Butler JE, et al. Immunology, 2000 May. PMID 10809967, Free PMC Article
  4. B-1 and B-2 B-cells in the pig cannot be differentiated by expression of CD5. Wilson SM, et al. Vet Immunol Immunopathol, 2007 Jan 15. PMID 17098293
  5. PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. Uenishi H, et al. Nucleic Acids Res, 2007 Jan. PMID 17145712, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

General protein information

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Preferred Names
IgG heavy chain
Names
Ig gamma 1b chain constant region
IgG heavy chian constant region
VDJ heavy chain
immunoglobulin gamma chain 3
immunoglobulin heavy chain gamma constant region
immunoglobulin heavy chain variable region
mutated immunoglobulin heavy chain

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_213828.1 → NP_998993.1  IgG heavy chain precursor

    See identical proteins and their annotated locations for NP_998993.1

    Status: PROVISIONAL

    Source sequence(s)
    AF062384
    UniProtKB/TrEMBL
    L8B0U3
    Conserved Domains (4) summary
    cd04981
    Location:23 → 145
    IgV_H; Immunoglobulin (Ig) heavy chain (H), variable (V) domain
    cd04985
    Location:151 → 244
    IgC_CH1; CH1 domain (first constant Ig domain of the heavy chain) in immunoglobulin
    smart00410
    Location:26 → 117
    IG_like; Immunoglobulin like
    cl11960
    Location:371 → 468
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NW_018084979.1 Reference Sscrofa11.1 Primary Assembly

    Range
    3676148..3841291 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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