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HAPLN1 hyaluronan and proteoglycan link protein 1 [ Gallus gallus (chicken) ]

Gene ID: 396475, updated on 13-Apr-2026
Symbol
HAPLN1provided by CGNC
Full Name
hyaluronan and proteoglycan link protein 1provided by CGNC
Primary source
CGNC:49825
See related
Ensembl:ENSGALG00010006730
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
CRTL1; HAPLN1L
Orthologs
all
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Try the new Transcripts and proteins table
See HAPLN1 in Genome Data Viewer
Location:
chromosome: Z
Exon count:
8
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) Z NC_052572.1 (63233947..63337452)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) Z NC_059536.1 (63233947..63337452)

Chromosome Z - NC_052572.1Genomic Context describing neighboring genes Neighboring gene E3 ubiquitin-protein ligase HRD1-like Neighboring gene EGF like repeats and discoidin domains 3 Neighboring gene uncharacterized LOC124417538 Neighboring gene uncharacterized LOC121108460 Neighboring gene uncharacterized LOC121108457 Neighboring gene uncharacterized LOC121108458 Neighboring gene uncharacterized LOC121108459 Neighboring gene versican Neighboring gene uncharacterized LOC121108461

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Structure of the chicken link protein gene: exons correlate with the protein domains. Kiss I, et al. Proc Natl Acad Sci U S A, 1987 Sep. PMID 3476955, Free PMC Article
  2. Complete amino acid sequence of chicken cartilage link protein deduced from cDNA clones. Deák F, et al. Proc Natl Acad Sci U S A, 1986 Jun. PMID 3459154, Free PMC Article
  3. Association between proteoglycans and matrix vesicles in the extracellular matrix of growth plate cartilage. Wu LN, et al. J Biol Chem, 1991 Jan 15. PMID 1985942
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  5. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables hyaluronic acid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
hyaluronan and proteoglycan link protein 1
Names
cartilage link protein
cartilage-linking protein 1
proteoglycan link protein

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_205482.3 → NP_990813.1  hyaluronan and proteoglycan link protein 1 precursor

    See identical proteins and their annotated locations for NP_990813.1

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000095
    UniProtKB/Swiss-Prot
    P07354
    UniProtKB/TrEMBL
    A0A8V0XZ15
    Conserved Domains (3) summary
    cd03518
    Location:160 → 254
    Link_domain_HAPLN_module_1; this link domain is found in the first link module of proteins similar to the vertebrate HAPLN (hyaluronan/HA and proteoglycan binding link) protein family which includes cartilage link protein. The link domain is a HA-binding domain. HAPLNs contain two ...
    cd03519
    Location:261 → 351
    Link_domain_HAPLN_module_2; this link domain is found in the second link module of proteins similar to the vertebrate HAPLN (hyaluronan/HA and proteoglycan binding link) protein family which includes cartilage link protein. The link domain is a HA-binding domain. HAPLNs contain two ...
    cd05877
    Location:44 → 162
    Ig_LP_like; Immunoglobulin (Ig)-like domain of human cartilage link protein (LP), and similar domains

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052572.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    63233947..63337452
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046905275.1 → XP_046761231.1  hyaluronan and proteoglycan link protein 1 isoform X1

    UniProtKB/Swiss-Prot
    P07354
    UniProtKB/TrEMBL
    A0A8V0XZ15

  2. XM_015280598.4 → XP_015136084.1  hyaluronan and proteoglycan link protein 1 isoform X1

    UniProtKB/Swiss-Prot
    P07354
    UniProtKB/TrEMBL
    A0A8V0XZ15
    Conserved Domains (3) summary
    cd03518
    Location:160 → 254
    Link_domain_HAPLN_module_1; this link domain is found in the first link module of proteins similar to the vertebrate HAPLN (hyaluronan/HA and proteoglycan binding link) protein family which includes cartilage link protein. The link domain is a HA-binding domain. HAPLNs contain two ...
    cd03519
    Location:261 → 351
    Link_domain_HAPLN_module_2; this link domain is found in the second link module of proteins similar to the vertebrate HAPLN (hyaluronan/HA and proteoglycan binding link) protein family which includes cartilage link protein. The link domain is a HA-binding domain. HAPLNs contain two ...
    cd05877
    Location:44 → 162
    Ig_LP_like; Immunoglobulin (Ig)-like domain of human cartilage link protein (LP), and similar domains

  3. XM_040655465.2 → XP_040511399.1  hyaluronan and proteoglycan link protein 1 isoform X1

    UniProtKB/Swiss-Prot
    P07354
    UniProtKB/TrEMBL
    A0A8V0XZ15
    Related
    ENSGALP00010009235.1, ENSGALT00010016066.1
    Conserved Domains (3) summary
    cd03518
    Location:160 → 254
    Link_domain_HAPLN_module_1; this link domain is found in the first link module of proteins similar to the vertebrate HAPLN (hyaluronan/HA and proteoglycan binding link) protein family which includes cartilage link protein. The link domain is a HA-binding domain. HAPLNs contain two ...
    cd03519
    Location:261 → 351
    Link_domain_HAPLN_module_2; this link domain is found in the second link module of proteins similar to the vertebrate HAPLN (hyaluronan/HA and proteoglycan binding link) protein family which includes cartilage link protein. The link domain is a HA-binding domain. HAPLNs contain two ...
    cd05877
    Location:44 → 162
    Ig_LP_like; Immunoglobulin (Ig)-like domain of human cartilage link protein (LP), and similar domains

  4. XM_025144694.3 → XP_025000462.1  hyaluronan and proteoglycan link protein 1 isoform X1

    UniProtKB/Swiss-Prot
    P07354
    UniProtKB/TrEMBL
    A0A8V0XZ15
    Related
    ENSGALP00010009234.1, ENSGALT00010016063.1
    Conserved Domains (3) summary
    cd03518
    Location:160 → 254
    Link_domain_HAPLN_module_1; this link domain is found in the first link module of proteins similar to the vertebrate HAPLN (hyaluronan/HA and proteoglycan binding link) protein family which includes cartilage link protein. The link domain is a HA-binding domain. HAPLNs contain two ...
    cd03519
    Location:261 → 351
    Link_domain_HAPLN_module_2; this link domain is found in the second link module of proteins similar to the vertebrate HAPLN (hyaluronan/HA and proteoglycan binding link) protein family which includes cartilage link protein. The link domain is a HA-binding domain. HAPLNs contain two ...
    cd05877
    Location:44 → 162
    Ig_LP_like; Immunoglobulin (Ig)-like domain of human cartilage link protein (LP), and similar domains

  5. XM_040655467.2 → XP_040511401.1  hyaluronan and proteoglycan link protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A8V0XZ15
    Conserved Domains (3) summary
    smart00406
    Location:48 → 134
    IGv; Immunoglobulin V-Type
    cd03518
    Location:152 → 246
    Link_domain_HAPLN_module_1; this link domain is found in the first link module of proteins similar to the vertebrate HAPLN (hyaluronan/HA and proteoglycan binding link) protein family which includes cartilage link protein. The link domain is a HA-binding domain. HAPLNs contain two ...
    cd03519
    Location:253 → 343
    Link_domain_HAPLN_module_2; this link domain is found in the second link module of proteins similar to the vertebrate HAPLN (hyaluronan/HA and proteoglycan binding link) protein family which includes cartilage link protein. The link domain is a HA-binding domain. HAPLNs contain two ...

  6. XM_040655466.2 → XP_040511400.1  hyaluronan and proteoglycan link protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8V0XZ15
    Conserved Domains (3) summary
    smart00406
    Location:48 → 134
    IGv; Immunoglobulin V-Type
    cd03518
    Location:152 → 246
    Link_domain_HAPLN_module_1; this link domain is found in the first link module of proteins similar to the vertebrate HAPLN (hyaluronan/HA and proteoglycan binding link) protein family which includes cartilage link protein. The link domain is a HA-binding domain. HAPLNs contain two ...
    cd03519
    Location:253 → 343
    Link_domain_HAPLN_module_2; this link domain is found in the second link module of proteins similar to the vertebrate HAPLN (hyaluronan/HA and proteoglycan binding link) protein family which includes cartilage link protein. The link domain is a HA-binding domain. HAPLNs contain two ...

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_059536.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    63233947..63337452
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046934898.1 → XP_046790854.1  hyaluronan and proteoglycan link protein 1 isoform X1

    UniProtKB/Swiss-Prot
    P07354
    UniProtKB/TrEMBL
    A0A8V0XZ15

  2. XM_046934900.1 → XP_046790856.1  hyaluronan and proteoglycan link protein 1 isoform X1

    UniProtKB/Swiss-Prot
    P07354
    UniProtKB/TrEMBL
    A0A8V0XZ15

  3. XM_046934901.1 → XP_046790857.1  hyaluronan and proteoglycan link protein 1 isoform X1

    UniProtKB/Swiss-Prot
    P07354
    UniProtKB/TrEMBL
    A0A8V0XZ15

  4. XM_046934899.1 → XP_046790855.1  hyaluronan and proteoglycan link protein 1 isoform X1

    UniProtKB/Swiss-Prot
    P07354
    UniProtKB/TrEMBL
    A0A8V0XZ15

  5. XM_046934903.1 → XP_046790859.1  hyaluronan and proteoglycan link protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A8V0XZ15

  6. XM_046934902.1 → XP_046790858.1  hyaluronan and proteoglycan link protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8V0XZ15
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P07354.1 GenPept UniProtKB/Swiss-Prot:P07354

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