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MYL4 myosin, light chain 4, alkali; atrial, embryonic [ Gallus gallus (chicken) ]

Gene ID: 396472, updated on 5-Aug-2022

Summary

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Official Symbol
MYL4provided by CGNC
Official Full Name
myosin, light chain 4, alkali; atrial, embryonicprovided by CGNC
Primary source
CGNC:49822
See related
Ensembl:ENSGALG00010021682
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
L23; MLC
Orthologs
human mouse all
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Genomic context

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See MYL4 in Genome Data Viewer
Location:
chromosome: 27
Exon count:
7
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 27 NC_052558.1 (2484639..2489847)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 27 NC_052599.1 (3702404..3707604)

Chromosome 27 - NC_052558.1Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 47 Neighboring gene DEAD-box helicase 42 Neighboring gene parathyroid hormone/parathyroid hormone-related peptide receptor-like Neighboring gene cell division cycle 27 Neighboring gene uncharacterized LOC101751949 Neighboring gene KAT8 regulatory NSL complex subunit 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A common myosin light chain is expressed in chicken embryonic skeletal, cardiac, and smooth muscles and in brain continuously from embryo to adult. Kawashima M, et al. J Biol Chem, 1987 Oct 25. PMID 3667580
  2. Isolation of the chick myosin alkali light chain gene expressed in embryonic gizzard muscle and transitional expression of the light chain gene family in vivo. Nabeshima Y, et al. J Mol Biol, 1988 Dec 5. PMID 3225843
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

See citations in PubMed for homologs of this gene provided by HomoloGene

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables actin monomer binding IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cardiac muscle contraction IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
Component Evidence Code Pubs
is_active_in A band IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
part_of myosin II complex IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 

General protein information

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Preferred Names
myosin light chain, embryonic
Names
myosin, light polypeptide 4, alkali; atrial, embryonic

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_205479.3 → NP_990810.2  myosin light chain, embryonic

    See identical proteins and their annotated locations for NP_990810.2

    Status: VALIDATED

    Source sequence(s)
    J02823, JAENSK010000363
    UniProtKB/Swiss-Prot
    P09540, Q90897
    Related
    ENSGALP00010031581.1, ENSGALT00010052675.1
    Conserved Domains (2) summary
    PTZ00184
    Location:39 → 184
    PTZ00184; calmodulin; Provisional
    cd00051
    Location:122 → 183
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052558.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    2484639..2489847
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046904335.1 → XP_046760291.1  myosin light chain, embryonic isoform X2

  2. XM_015299308.3 → XP_015154794.2  myosin light chain, embryonic isoform X1

    Conserved Domains (1) summary
    PTZ00184
    Location:168 → 310
    PTZ00184; calmodulin; Provisional

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052599.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    3702404..3707604
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046933306.1 → XP_046789262.1  myosin light chain, embryonic isoform X2

  2. XM_046933305.1 → XP_046789261.1  myosin light chain, embryonic isoform X1

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P09540.1 GenPept UniProtKB/Swiss-Prot:P09540

Gene LinkOut

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