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NGF nerve growth factor [ Gallus gallus (chicken) ]

Gene ID: 396466, updated on 5-Jun-2022

Summary

Symbol
NGFprovided by CGNC
Full Name
nerve growth factorprovided by CGNC
Primary source
CGNC:1838
See related
EnsemblRapid:ENSGALG00010025423
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
NGFB; beta-NGF
Orthologs
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Genomic context

See NGF in Genome Data Viewer
Location:
chromosome: 26
Exon count:
5
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 26 NC_052557.1 (4068260..4091234, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 26 NC_052598.1 (4036097..4059075, complement)

Chromosome 26 - NC_052557.1Genomic Context describing neighboring genes Neighboring gene bile acid receptor-like Neighboring gene synaptonemal complex protein 1 Neighboring gene tetraspanin 2 Neighboring gene thyroid stimulating hormone beta Neighboring gene uncharacterized LOC101747934 Neighboring gene Fanconi anemia complementation group E

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables growth factor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables nerve growth factor receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in memory IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in modulation of chemical synaptic transmission IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in negative regulation of neuron apoptotic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in nerve development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in nerve growth factor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in neuron projection morphogenesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in peripheral nervous system development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in positive regulation of collateral sprouting IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in positive regulation of peptidyl-serine phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of neuron differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in transmembrane receptor protein tyrosine kinase signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in axon IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in dendrite IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in synaptic vesicle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
beta-nerve growth factor
Names
nerve growth factor (beta polypeptide)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001293108.1NP_001280037.1  beta-nerve growth factor precursor

    See identical proteins and their annotated locations for NP_001280037.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    BU313448, BU337330, CD217960
    UniProtKB/TrEMBL
    A0A140T8F7
    Related
    ENSGALP00010038375.1, ENSGALT00010062094.1
    Conserved Domains (1) summary
    pfam00243
    Location:128236
    NGF; Nerve growth factor family
  2. NM_001293109.2NP_001280038.1  beta-nerve growth factor precursor

    See identical proteins and their annotated locations for NP_001280038.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    JAENSK010000356
    UniProtKB/TrEMBL
    A0A140T8F7
    Related
    ENSGALP00010038353.1, ENSGALT00010062072.1
    Conserved Domains (1) summary
    pfam00243
    Location:128236
    NGF; Nerve growth factor family

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052557.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    4068260..4091234 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015298897.4XP_015154383.1  beta-nerve growth factor isoform X1

    UniProtKB/TrEMBL
    A0A140T8F7
    Conserved Domains (1) summary
    pfam00243
    Location:128236
    NGF; Nerve growth factor family
  2. XM_046904106.1XP_046760062.1  beta-nerve growth factor isoform X1

    Related
    ENSGALP00010038369.1, ENSGALT00010062088.1

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052598.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    4036097..4059075 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046932898.1XP_046788854.1  beta-nerve growth factor isoform X1

  2. XM_046932897.1XP_046788853.1  beta-nerve growth factor isoform X1