EXFABP extracellular fatty acid-binding protein [Gallus gallus (chicken)] - Gene

Summary

Official Symbol: EXFABPprovided by CGNC
Official Full Name: extracellular fatty acid-binding proteinprovided by CGNC
Primary source: CGNC:49786
See related: Ensembl:ENSGALG00010028912
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as: LCN8; P20K; LCN15; EX-FABP
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Genomic context

Location:: chromosome: 17

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	17	NC_052548.1 (1177672..1180688, complement)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	17	NC_052589.1 (585587..588602, complement)

Chromosome 17 - NC_052548.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The Ex-FABP gene could be a candidate locus or linked to a QTL that significantly affects fatty deposition and metabolism in chicken.
Title: Polymorphisms in chicken extracellular fatty acid binding protein gene.
Ex-FABP binds long chain unsaturated fatty acids with high affinity in chondrocyte and myoblast cultures.
Title: Ex-FABP, extracellular fatty acid binding protein, is a stress lipocalin expressed during chicken embryo development.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by GOA

Function	Evidence Code	Pubs
enables arachidonic acid binding	IDA Inferred from Direct Assay more info	PubMed
enables fatty acid binding	IDA Inferred from Direct Assay more info	PubMed
enables linoleic acid binding	IDA Inferred from Direct Assay more info	PubMed
enables oleic acid binding	IDA Inferred from Direct Assay more info	PubMed
enables stearic acid binding	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
involved_in acute-phase response	IEP Inferred from Expression Pattern more info	PubMed
involved_in acute-phase response	TAS Traceable Author Statement more info	PubMed
involved_in apoptotic process	IDA Inferred from Direct Assay more info	PubMed
involved_in apoptotic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in cell differentiation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in cell population proliferation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in cellular lipid metabolic process	NAS Non-traceable Author Statement more info	PubMed
involved_in cellular response to linoleic acid	IDA Inferred from Direct Assay more info	PubMed
involved_in chondrocyte differentiation	IEP Inferred from Expression Pattern more info	PubMed
involved_in chondrocyte hypertrophy	IEP Inferred from Expression Pattern more info	PubMed
involved_in defense response to bacterium	IEA Inferred from Electronic Annotation more info
involved_in embryo development ending in birth or egg hatching	TAS Traceable Author Statement more info	PubMed
involved_in fatty acid homeostasis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in fatty acid transport	IC Inferred by Curator more info	PubMed
involved_in fatty acid transport	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in fatty acid transport	NAS Non-traceable Author Statement more info	PubMed
involved_in heart development	IEP Inferred from Expression Pattern more info	PubMed
involved_in inflammatory response	IDA Inferred from Direct Assay more info	PubMed
involved_in inflammatory response	IEP Inferred from Expression Pattern more info	PubMed
involved_in innate immune response	IEA Inferred from Electronic Annotation more info
involved_in long-chain fatty acid transport	TAS Traceable Author Statement more info	PubMed
involved_in muscle cell development	TAS Traceable Author Statement more info	PubMed
involved_in negative regulation of apoptotic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of cell population proliferation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of chondrocyte differentiation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of myoblast differentiation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of myotube differentiation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to corticosterone	IDA Inferred from Direct Assay more info	PubMed
involved_in response to cytokine	IEP Inferred from Expression Pattern more info	PubMed
involved_in response to linoleic acid	IDA Inferred from Direct Assay more info	PubMed
involved_in response to lipopolysaccharide	IEP Inferred from Expression Pattern more info	PubMed
involved_in response to lipopolysaccharide	TAS Traceable Author Statement more info	PubMed
involved_in response to toxic substance	TAS Traceable Author Statement more info	PubMed
involved_in response to xenobiotic stimulus	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular space	IDA Inferred from Direct Assay more info	PubMed
located_in extracellular space	NAS Non-traceable Author Statement more info	PubMed
located_in extracellular space	TAS Traceable Author Statement more info	PubMed

General protein information

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Preferred Names: extracellular fatty acid-binding protein

Names: lipocalin 15; lipocalin 8; quiescence-specific protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_205422.2 → NP_990753.2 extracellular fatty acid-binding protein precursor

Status: PROVISIONAL

Source sequence(s)

JAENSK010000308

UniProtKB/TrEMBL

A0A1D5NW85

Related

ENSGALP00010043073.1, ENSGALT00010069947.1

Conserved Domains (1) summary

cd19439
Location:27 → 168

lipocalin_Ex-FABP-like; extracellular fatty acid-binding protein

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052548.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

1177672..1180688 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)