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LGALS7 galectin 7 [ Homo sapiens (human) ]

Gene ID: 3963, updated on 9-Jul-2017
Official Symbol
LGALS7provided by HGNC
Official Full Name
galectin 7provided by HGNC
Primary source
HGNC:HGNC:6568
See related
Ensembl:ENSG00000205076 MIM:600615; Vega:OTTHUMG00000182606
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
GAL7; LGALS7A
Summary
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Differential and in situ hybridization studies indicate that this lectin is specifically expressed in keratinocytes and found mainly in stratified squamous epithelium. A duplicate copy of this gene (GeneID:653499) is found adjacent to, but on the opposite strand on chromosome 19. [provided by RefSeq, Jul 2008]
Orthologs
Location:
19q13.2
Exon count:
4
Annotation release Status Assembly Chr Location
108 current GRCh38.p7 (GCF_000001405.33) 19 NC_000019.10 (38770968..38773517, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (39261608..39264157, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene actinin alpha 4 Neighboring gene uncharacterized LOC107985291 Neighboring gene calpain 12 Neighboring gene galectin 7B Neighboring gene galectin 4

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Preferred Names
galectin-7
Names
lectin, galactoside-binding, soluble, 7

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_002307.3NP_002298.1  galectin-7

    See identical proteins and their annotated locations for NP_002298.1

    Status: REVIEWED

    Source sequence(s)
    BP225960
    Consensus CDS
    CCDS33012.1
    UniProtKB/Swiss-Prot
    P47929
    Related
    ENSP00000367891.3, OTTHUMP00000269637, ENST00000378626.4, OTTHUMT00000462636
    Conserved Domains (1) summary
    smart00908
    Location:11133
    Gal-bind_lectin; Galactoside-binding lectin

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p7 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p7 Primary Assembly

    Range
    38770968..38773517 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p7 PATCHES

Genomic

  1. NW_014040929.1 Reference GRCh38.p7 PATCHES

    Range
    180608..183157 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CHM1_1.1

Genomic

  1. NC_018930.2 Alternate CHM1_1.1

    Range
    39280322..39282871
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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