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PARP1 poly(ADP-ribose) polymerase 1 [ Gallus gallus (chicken) ]

Gene ID: 396199, updated on 6-May-2021

Summary

Official Symbol
PARP1provided by CGNC
Official Full Name
poly(ADP-ribose) polymerase 1provided by CGNC
Primary source
CGNC:7010
See related
Ensembl:ENSGALG00000009228
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
ADPRT; ARTD1; PARP-1
Orthologs
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Genomic context

See PARP1 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
23
Annotation release Status Assembly Chr Location
105 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 3 NC_052534.1 (16710070..16740072)
105 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.1) 3 NC_052575.1 (16624599..16654483)
104 previous assembly GRCg6a (GCF_000002315.5) 3 NC_006090.5 (17119696..17149617)
103 previous assembly Gallus_gallus-5.0 (GCF_000002315.4) 3 NC_006090.4 (17031346..17061269)

Chromosome 3 - NC_052534.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121110399 Neighboring gene uncharacterized LOC107052966 Neighboring gene lin-9 DREAM MuvB core complex component Neighboring gene uncharacterized LOC121113190 Neighboring gene Mix paired-like homeobox

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables NAD binding IEA
Inferred from Electronic Annotation
more info
 
enables NAD+ ADP-ribosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables protein ADP-ribosylase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in ATP generation from poly-ADP-D-ribose ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in DNA ADP-ribosylation ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in DNA repair IEA
Inferred from Electronic Annotation
more info
 
involved_in peptidyl-glutamic acid poly-ADP-ribosylation ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in peptidyl-serine ADP-ribosylation ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in positive regulation of double-strand break repair via homologous recombination ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in protein auto-ADP-ribosylation ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in protein poly-ADP-ribosylation IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
located_in chromosome IEA
Inferred from Electronic Annotation
more info
 
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
poly [ADP-ribose] polymerase 1
Names
ADP-ribosyltransferase NAD(+)
ADP-ribosyltransferase diphtheria toxin-like 1
ADPRT 1
DNA ADP-ribosyltransferase PARP1
NAD(+) ADP-ribosyltransferase 1
TCDD-inducible poly(ADP-ribose) polymerase
poly (ADP-ribose) polymerase family, member 1
poly[ADP-ribose] synthase 1
poly[ADP-ribose] synthetase 1
protein poly-ADP-ribosyltransferase PARP1
NP_990594.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_205263.2NP_990594.2  poly [ADP-ribose] polymerase 1

    Status: VALIDATED

    Source sequence(s)
    AADN05000005
    Related
    ENSGALP00000038037.4, ENSGALT00000038829.4
    Conserved Domains (6) summary
    cd08001
    Location:540642
    WGR_PARP1_like; WGR domain of poly(ADP-ribose) polymerase 1 and similar proteins
    PLN03123
    Location:61007
    PLN03123; poly [ADP-ribose] polymerase; Provisional
    cd01437
    Location:6591003
    parp_like; Poly(ADP-ribose) polymerase (parp) catalytic domain catalyses the covalent attachment of ADP-ribose units from NAD+ to itself and to a limited number of other DNA binding proteins, which decreases their affinity for DNA. Poly(ADP-ribose) polymerase is a ...
    pfam00533
    Location:382458
    BRCT; BRCA1 C Terminus (BRCT) domain
    pfam00645
    Location:1285
    zf-PARP; Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region
    pfam08063
    Location:279330
    PADR1; PADR1 (NUC008) domain

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052534.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    16710070..16740072
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052575.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    16624599..16654483
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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