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ITGB2 integrin subunit beta 2 [ Gallus gallus (chicken) ]

Gene ID: 396181, updated on 3-Dec-2024
Symbol
ITGB2provided by CGNC
Full Name
integrin subunit beta 2provided by CGNC
Primary source
CGNC:49690
See related
Ensembl:ENSGALG00010014976
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
CD18
Orthologs
human mouse all
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See ITGB2 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
17
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 7 NC_052538.1 (7210321..7222404, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 7 NC_052579.1 (7144680..7156774, complement)

Chromosome 7 - NC_052538.1Genomic Context describing neighboring genes Neighboring gene C21orf58 homolog Neighboring gene kynurenine 3-monooxygenase Neighboring gene family with sequence similarity 207 member A Neighboring gene nascent polypeptide-associated complex subunit alpha, muscle-specific form-like Neighboring gene adenosine deaminase, RNA specific B1

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Cloning and expression of the chicken CD18 cDNA. Bilsland CA, et al. J Leukoc Biol, 1994 Apr. PMID 7908319
  2. Splenic gene expression profiling in White Leghorn layer inoculated with the Salmonella enterica serovar Enteritidis. Wu G, et al. Anim Genet, 2015 Dec. PMID 26358731
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables amyloid-beta binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables integrin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell adhesion mediated by integrin IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-matrix adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in integrin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cell surface IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in focal adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of integrin complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
integrin beta-2
Names
integrin beta 2 subunit
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001396549.1 → NP_001383478.1  integrin beta-2 isoform 1 precursor

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000235
    UniProtKB/TrEMBL
    A0A8V0YJ20, Q92070
    Related
    ENSGALP00010020915.1, ENSGALT00010036026.1
    Conserved Domains (1) summary
    smart00187
    Location:34 → 450
    INB; Integrin beta subunits (N-terminal portion of extracellular region)

  2. NM_205251.2 → NP_990582.2  integrin beta-2 isoform 2 precursor

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000235
    UniProtKB/TrEMBL
    Q92070
    Related
    ENSGALP00010020920.1, ENSGALT00010036033.1
    Conserved Domains (1) summary
    smart00187
    Location:34 → 450
    INB; Integrin beta subunits (N-terminal portion of extracellular region)

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052538.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    7210321..7222404 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015289135.4 → XP_015144621.1  integrin beta-2 isoform X2

    UniProtKB/TrEMBL
    A0A8V0YJ29, Q92070
    Related
    ENSGALP00010020925.1, ENSGALT00010036041.1
    Conserved Domains (3) summary
    pfam00362
    Location:63 → 479
    Integrin_beta; Integrin, beta chain
    pfam07965
    Location:653 → 731
    Integrin_B_tail; Integrin beta tail domain
    pfam08725
    Location:760 → 799
    Integrin_b_cyt; Integrin beta cytoplasmic domain

  2. XM_015289134.4 → XP_015144620.1  integrin beta-2 isoform X1

    UniProtKB/TrEMBL
    Q92070
    Conserved Domains (3) summary
    pfam00362
    Location:63 → 479
    Integrin_beta; Integrin, beta chain
    pfam07965
    Location:653 → 736
    Integrin_B_tail; Integrin beta tail domain
    pfam08725
    Location:765 → 804
    Integrin_b_cyt; Integrin beta cytoplasmic domain

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052579.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    7144680..7156774 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046921141.1 → XP_046777097.1  integrin beta-2 isoform X2

    UniProtKB/TrEMBL
    A0A8V0YJ29, Q92070

  2. XM_046921140.1 → XP_046777096.1  integrin beta-2 isoform X1

    UniProtKB/TrEMBL
    Q92070
Nucleotide Protein Strain
Heading Accession and Version

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