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NR1D2 nuclear receptor subfamily 1 group D member 2 [ Gallus gallus (chicken) ]

Gene ID: 396125, updated on 14-Feb-2019

Summary

Symbol
NR1D2provided by CGNC
Full Name
nuclear receptor subfamily 1 group D member 2provided by CGNC
Primary source
CGNC:49661
See related
Ensembl:ENSGALG00000011291
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
REV-ERBB
Summary
This gene encodes a member of the nuclear hormone receptor family, specifically the NR1 subfamily of receptors. The encoded protein functions as a transcriptional repressor and may play a role in circadian rhythms and carbohydrate and lipid metabolism. [provided by RefSeq, Feb 2014]
Orthologs

Genomic context

See NR1D2 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
8
Annotation release Status Assembly Chr Location
104 current GRCg6a (GCF_000002315.5) 2 NC_006089.5 (37149585..37175030)
103 previous assembly Gallus_gallus-5.0 (GCF_000002315.4) 2 NC_006089.4 (37343012..37370894)
102 previous assembly Gallus_gallus-4.0 (GCF_000002315.3) 2 NC_006089.3 (37787391..37809860)

Chromosome 2 - NC_006089.5Genomic Context describing neighboring genes Neighboring gene ubiquitin conjugating enzyme E2 E1 Neighboring gene NFKB inhibitor interacting Ras like 1 Neighboring gene ribosomal protein L15 Neighboring gene thyroid hormone receptor beta Neighboring gene uncharacterized LOC107052539 Neighboring gene retinoic acid receptor beta Neighboring gene uncharacterized LOC112531715

Genomic regions, transcripts, and products

Pathways from BioSystems

  • Nuclear Receptors, organism-specific biosystem (from WikiPathways)
    Nuclear Receptors, organism-specific biosystemNuclear receptors are a class of proteins found within the interior of cells that are responsible for sensing the presence of steroid and thyroid hormones and certain other molecules. In response, th...

General gene information

Homology

General protein information

Preferred Names
nuclear receptor subfamily 1 group D member 2
Names
Rev-erb-beta

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_205205.2NP_990536.2  nuclear receptor subfamily 1 group D member 2 precursor

    Status: VALIDATED

    Source sequence(s)
    CR382426, X80258
    UniProtKB/TrEMBL
    A0A1D6UPS4, Q90970
    Related
    ENSGALP00000030528.4, ENSGALT00000031164.5
    Conserved Domains (2) summary
    cd06940
    Location:398585
    NR_LBD_REV_ERB; The ligand binding domain of REV-ERB receptors, members of the nuclear receptor superfamily
    cd07166
    Location:111199
    NR_DBD_REV_ERB; DNA-binding domain of REV-ERB receptor-like is composed of two C4-type zinc fingers

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCg6a Primary Assembly

Genomic

  1. NC_006089.5 Reference GRCg6a Primary Assembly

    Range
    37149585..37175030
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015281306.2XP_015136792.1  nuclear receptor subfamily 1 group D member 2 isoform X1

    Conserved Domains (2) summary
    cd06940
    Location:383570
    NR_LBD_REV_ERB; The ligand binding domain of REV-ERB receptors, members of the nuclear receptor superfamily
    cd07166
    Location:96184
    NR_DBD_REV_ERB; DNA-binding domain of REV-ERB receptor-like is composed of two C4-type zinc fingers
  2. XM_015281307.2XP_015136793.1  nuclear receptor subfamily 1 group D member 2 isoform X2

    Conserved Domains (2) summary
    cd07166
    Location:96184
    NR_DBD_REV_ERB; DNA-binding domain of REV-ERB receptor-like is composed of two C4-type zinc fingers
    cl11397
    Location:383438
    NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators
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