U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

BMPR1B bone morphogenetic protein receptor type 1B [ Gallus gallus (chicken) ]

Gene ID: 396030, updated on 5-Sep-2025
Official Symbol
BMPR1Bprovided by CGNC
Official Full Name
bone morphogenetic protein receptor type 1Bprovided by CGNC
Primary source
CGNC:49616
See related
Ensembl:ENSGALG00010004337
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
RPK-1
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table
See BMPR1B in Genome Data Viewer
Location:
chromosome: 4
Exon count:
18
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 4 NC_052535.1 (57870447..58109209)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 4 NC_052576.1 (57873384..58112079)

Chromosome 4 - NC_052535.1Genomic Context describing neighboring genes Neighboring gene mitochondrial calcium uniporter dominant negative beta subunit Neighboring gene PDZ and LIM domain 5 Neighboring gene unc-5 netrin receptor C Neighboring gene microRNA 122b Neighboring gene uncharacterized LOC121110597

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Evidence against involvement of Bmp receptor 1b signaling in fate specification of the chick mesencephalic alar plate at HH16. Bobak N, et al. Neurosci Lett, 2009 Sep 25. PMID 19539011
  2. A new receptor protein kinase from chick embryo related to type II receptor for TGF-beta. Sumitomo S, et al. DNA Seq, 1993. PMID 8400359
  3. Altered BMP signaling disrupts chick diencephalic development. Lim Y, et al. Mech Dev, 2005 Apr. PMID 15804571
  4. Bone morphogenetic protein signaling is required for maintenance of differentiated phenotype, control of proliferation, and hypertrophy in chondrocytes. Enomoto-Iwamoto M, et al. J Cell Biol, 1998 Jan 26. PMID 9442116, Free PMC Article
  5. BMP signaling during bone pattern determination in the developing limb. Kawakami Y, et al. Development, 1996 Nov. PMID 8951071

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The finding that retinal gene expression for BMP2, 4, 7 and their receptors are not affected by short-term optical defocus contrasts with previous observations of sign-dependent expression changes for the same genes in the RPE.
    Title: Differential gene expression of BMP2 and BMP receptors in chick retina & choroid induced by imposed optical defocus.
  2. Type Ib BMP receptors mediate the rate of commissural axon extension through inhibition of cofilin activity
    Title: Type Ib BMP receptors mediate the rate of commissural axon extension through inhibition of cofilin activity.
  3. Whereas the importance of Bmp signaling for dorsal differentiation in the spinal cord is well established, it appears to play a less prominent role in the dorsal specification of the developing mesencephalon during the same developmental stages.
    Title: Evidence against involvement of Bmp receptor 1b signaling in fate specification of the chick mesencephalic alar plate at HH16.
  4. BMP signaling via Bmpr1a and Bmpr1b, is sufficient to modify nuclear organization in the chick diencephalon
    Title: Altered BMP signaling disrupts chick diencephalic development.
Submit: New GeneRIF Correction

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables SMAD binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transforming growth factor beta receptor activity, type I IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in BMP signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to growth factor stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in dorsal/ventral pattern formation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
bone morphogenetic protein receptor type-1B
Names
ALK-6
BMP type-1B receptor
BMPR-1B
SKR6
activin receptor-like kinase 6
bone morphogenetic protein receptor, type IB
receptor protein kinase
serine/threonine-protein kinase receptor R6
NP_001384808.1
NP_990463.2
XP_015131639.1
XP_040554669.1
XP_040554670.1
XP_040554671.1
XP_040554672.1
XP_046771504.1
XP_046771505.1
XP_046771506.1
XP_046771507.1

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001397879.1 → NP_001384808.1  bone morphogenetic protein receptor type-1B precursor

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000074
    UniProtKB/Swiss-Prot
    Q05438
    UniProtKB/TrEMBL
    F1NTD3
    Related
    ENSGALP00010005912.1, ENSGALT00010010118.1
    Conserved Domains (3) summary
    cd14219
    Location:198 → 502
    STKc_BMPR1b; Catalytic domain of the Serine/Threonine Kinase, Bone Morphogenetic Protein Type IB
    pfam01064
    Location:34 → 106
    Activin_recp; Activin types I and II receptor domain
    pfam08515
    Location:175 → 202
    TGF_beta_GS; Transforming growth factor beta type I GS-motif

  2. NM_205132.2 → NP_990463.2  bone morphogenetic protein receptor type-1B precursor

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000074
    UniProtKB/Swiss-Prot
    Q05438
    UniProtKB/TrEMBL
    F1NTD3
    Conserved Domains (3) summary
    cd14219
    Location:198 → 502
    STKc_BMPR1b; Catalytic domain of the Serine/Threonine Kinase, Bone Morphogenetic Protein Type IB
    pfam01064
    Location:34 → 106
    Activin_recp; Activin types I and II receptor domain
    pfam08515
    Location:175 → 202
    TGF_beta_GS; Transforming growth factor beta type I GS-motif

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052535.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    57870447..58109209
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040698737.2 → XP_040554671.1  bone morphogenetic protein receptor type-1B isoform X1

    UniProtKB/Swiss-Prot
    Q05438
    UniProtKB/TrEMBL
    F1NTD3
    Conserved Domains (3) summary
    cd14219
    Location:198 → 502
    STKc_BMPR1b; Catalytic domain of the Serine/Threonine Kinase, Bone Morphogenetic Protein Type IB
    pfam01064
    Location:34 → 106
    Activin_recp; Activin types I and II receptor domain
    pfam08515
    Location:175 → 202
    TGF_beta_GS; Transforming growth factor beta type I GS-motif

  2. XM_040698735.2 → XP_040554669.1  bone morphogenetic protein receptor type-1B isoform X1

    UniProtKB/Swiss-Prot
    Q05438
    UniProtKB/TrEMBL
    F1NTD3
    Conserved Domains (3) summary
    cd14219
    Location:198 → 502
    STKc_BMPR1b; Catalytic domain of the Serine/Threonine Kinase, Bone Morphogenetic Protein Type IB
    pfam01064
    Location:34 → 106
    Activin_recp; Activin types I and II receptor domain
    pfam08515
    Location:175 → 202
    TGF_beta_GS; Transforming growth factor beta type I GS-motif

  3. XM_040698736.2 → XP_040554670.1  bone morphogenetic protein receptor type-1B isoform X1

    UniProtKB/Swiss-Prot
    Q05438
    UniProtKB/TrEMBL
    F1NTD3
    Conserved Domains (3) summary
    cd14219
    Location:198 → 502
    STKc_BMPR1b; Catalytic domain of the Serine/Threonine Kinase, Bone Morphogenetic Protein Type IB
    pfam01064
    Location:34 → 106
    Activin_recp; Activin types I and II receptor domain
    pfam08515
    Location:175 → 202
    TGF_beta_GS; Transforming growth factor beta type I GS-motif

  4. XM_040698738.2 → XP_040554672.1  bone morphogenetic protein receptor type-1B isoform X1

    UniProtKB/Swiss-Prot
    Q05438
    UniProtKB/TrEMBL
    F1NTD3
    Conserved Domains (3) summary
    cd14219
    Location:198 → 502
    STKc_BMPR1b; Catalytic domain of the Serine/Threonine Kinase, Bone Morphogenetic Protein Type IB
    pfam01064
    Location:34 → 106
    Activin_recp; Activin types I and II receptor domain
    pfam08515
    Location:175 → 202
    TGF_beta_GS; Transforming growth factor beta type I GS-motif

  5. XM_015276153.4 → XP_015131639.1  bone morphogenetic protein receptor type-1B isoform X1

    UniProtKB/Swiss-Prot
    Q05438
    UniProtKB/TrEMBL
    F1NTD3
    Related
    ENSGALP00010005905.1, ENSGALT00010010108.1
    Conserved Domains (3) summary
    cd14219
    Location:198 → 502
    STKc_BMPR1b; Catalytic domain of the Serine/Threonine Kinase, Bone Morphogenetic Protein Type IB
    pfam01064
    Location:34 → 106
    Activin_recp; Activin types I and II receptor domain
    pfam08515
    Location:175 → 202
    TGF_beta_GS; Transforming growth factor beta type I GS-motif

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052576.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    57873384..58112079
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046915550.1 → XP_046771506.1  bone morphogenetic protein receptor type-1B isoform X1

    UniProtKB/Swiss-Prot
    Q05438

  2. XM_046915551.1 → XP_046771507.1  bone morphogenetic protein receptor type-1B isoform X1

    UniProtKB/Swiss-Prot
    Q05438

  3. XM_046915549.1 → XP_046771505.1  bone morphogenetic protein receptor type-1B isoform X1

    UniProtKB/Swiss-Prot
    Q05438

  4. XM_046915548.1 → XP_046771504.1  bone morphogenetic protein receptor type-1B isoform X1

    UniProtKB/Swiss-Prot
    Q05438
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q05438.1 GenPept UniProtKB/Swiss-Prot:Q05438

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.